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Side Effects of Propylthiouracil

Andrew Bellingham

Andrew Bellingham

Pharmacist | 20+ Years | BPharm | Dip Clin Pharm

Propylthiouracil, commonly known as PTU, is a medication used in the treatment of hyperthyroidism.

Having an excess of thyroid hormones in your system can lead to a wide range of distressing symptoms like unexplained weight loss, mood swings and increased heart rate (palpitations).

Common Side Effects of Propylthiouracil

Taking Propylthiouracil (PTU) might cause some side effects in a few people. These can include:

  • Nausea
  • Upset stomach
  • Vomiting
  • Headaches
  • Drowsiness & dizziness
  • Joint or muscle pain
  • Skin rash


Not everyone will experience these side effects, and they can vary in how severe they are. If they don’t go away by themselves or make you particularly uncomfortable, consult your GP or pharmacist for further guidance.

Serious Liver Problems - Propylthiouracil

Taking propylthiouracil can cause serious liver problems for some people. If you notice any of the following side effects, you should speak with your doctor immediately: 

  • Jaundice (yellow skin or eyes)
  • Dark urine
  • Severe itching
  • Feeling generally unwell

Order Your Prescription Online with Healthera

If you’ve been prescribed propylthiouracil to treat an overactive thyroid issue by your GP, you can place your order online from your local pharmacy with Healthera.

It only takes a few minutes to set up your prescription for collection or home delivery. 

To get started, simply click the button below:

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