How does glimepiride work?
Glimepiride stimulates the pancreas to release more insulin, helping lower blood sugar levels and improve glucose control.
What is glimepiride used to treat?
Glimepiride is commonly prescribed for:
- Type 2 diabetes (to improve blood sugar control when diet and exercise alone are not enough)
- Combination therapy (often used with other diabetes medications such as metformin or insulin)
Who can take glimepiride?
Glimepiride is suitable for most adults with type 2 diabetes, as prescribed by a doctor.
Who might not be able to take glimepiride?
Glimepiride may not be suitable if you:
- Have type 1 diabetes (it is not effective for this type)
- Have severe kidney or liver disease
- Have a history of hypoglycaemia (low blood sugar)
- Are taking other medications that affect blood sugar levels
Can I take glimepiride if I’m pregnant or breastfeeding?
Glimepiride isn’t usually recommended during pregnancy or breastfeeding. Speak to your doctor about safer alternatives.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is glimepiride?
Glimepiride is highly effective at lowering blood sugar levels when combined with a healthy diet and exercise.
What should I do if I take too much?
Taking too much glimepiride can cause low blood sugar (hypoglycaemia), which may lead to dizziness, sweating, or confusion. If you experience symptoms, eat or drink something sugary and seek medical help if necessary.
What dose of glimepiride is usually taken?
- For type 2 diabetes: Starting dose of 1mg to 2mg once daily, increasing if needed (maximum dose 6mg daily)
Your doctor will determine the correct dose based on your condition.
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What are the side effects of glimepiride?
Common side effects include:
- Low blood sugar (hypoglycaemia)
- Weight gain
- Nausea or upset stomach
- Dizziness or headache
Serious side effects, such as severe hypoglycaemia, liver problems, or allergic reactions, require urgent medical attention.
How should I take glimepiride?
Glimepiride is taken as tablets, usually once daily, with food to reduce the risk of low blood sugar.
When should glimepiride be taken?
Glimepiride should be taken at the same time each day, typically with breakfast or the first main meal of the day.
What are the brand names for glimepiride?
Glimepiride is available as a generic medicine, but some branded versions include:
- Amaryl
- Glimiset
Final thoughts
Glimepiride is an effective medication for managing type 2 diabetes, but it should be taken exactly as prescribed. Regular blood sugar monitoring is recommended. If side effects occur, speak to your doctor or pharmacist.
