Gliclazide

Gliclazide is a medication used to treat type 2 diabetes. It helps lower blood sugar levels by stimulating insulin production in the pancreas. If you’ve been prescribed gliclazide, here’s what you need to know.

What is gliclazide?

Gliclazide is a sulfonylurea medication that helps control blood sugar levels in people with type 2 diabetes.

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How does gliclazide work?

Gliclazide stimulates the pancreas to release more insulin, which helps lower blood sugar levels and manage diabetes effectively.

What is gliclazide used to treat?

Gliclazide is commonly prescribed for:

  • Type 2 diabetes (when diet and exercise alone are not enough to control blood sugar levels)
  • Preventing complications of diabetes, such as kidney disease, nerve damage, and vision problems

Who can take gliclazide?

Gliclazide is suitable for most adults with type 2 diabetes, as prescribed by a doctor.

Who might not be able to take gliclazide?

Gliclazide may not be suitable if you:

  • Have type 1 diabetes or diabetic ketoacidosis
  • Have severe liver or kidney disease
  • Are pregnant or breastfeeding (unless advised by a doctor)
  • Have a history of severe hypoglycaemia (low blood sugar)

Can I take gliclazide if I’m pregnant or breastfeeding?

Gliclazide isn’t usually recommended during pregnancy or breastfeeding. Your doctor may suggest an alternative medication such as insulin.

What if I miss a dose?

If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.

How effective is gliclazide?

Gliclazide is highly effective at lowering blood sugar levels when taken as prescribed, especially when combined with a healthy diet and regular exercise.

What should I do if I take too much?

Taking too much gliclazide can cause dangerously low blood sugar (hypoglycaemia), leading to symptoms such as dizziness, sweating, confusion, or fainting. If you experience these symptoms, eat or drink something sugary immediately and seek medical help if symptoms persist.

What dose of gliclazide is usually taken?

  • Starting dose: 40mg to 80mg once daily, usually before breakfast
  • Maintenance dose: Up to 320mg daily, divided into one or two doses
  • Modified-release tablets: 30mg to 120mg once daily

Your doctor will determine the correct dose based on your blood sugar levels.

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What are the side effects of gliclazide?

Common side effects include:

  • Low blood sugar (hypoglycaemia)
  • Nausea or upset stomach
  • Weight gain
  • Headaches

Serious side effects, such as severe hypoglycaemia or liver problems, require urgent medical attention.

How should I take gliclazide?

Gliclazide is taken as tablets, once or twice daily, usually with food to reduce the risk of low blood sugar.

When should gliclazide be taken?

Gliclazide should be taken before or with a meal, typically breakfast, to help regulate blood sugar throughout the day.

What are the brand names for gliclazide?

Gliclazide is available as a generic medicine, but some branded versions include:

  • Diamicron
  • Zicron

Final thoughts

Gliclazide is an effective medication for managing type 2 diabetes, but it should be taken exactly as prescribed to avoid low blood sugar. If you experience side effects or need to adjust your dose, speak to your doctor or pharmacist.

Always consult a medical professional
This article is for informational purposes only and is not a substitute for medical advice. Always consult a healthcare professional before starting, stopping or changing any medication. If you have concerns about your medication or experience side effects, speak to your doctor or pharmacist immediately.

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