How does colchicine work?
Colchicine reduces the build-up of uric acid crystals in the joints, preventing inflammation and relieving pain during a gout attack.
What is colchicine used to treat?
Colchicine is commonly prescribed for:
- Gout attacks (to reduce pain and swelling in joints)
- Preventing future gout attacks
- Familial Mediterranean fever (FMF) (a rare genetic condition causing inflammation)
Who can take colchicine?
Colchicine is suitable for most adults who need treatment for gout or other inflammatory conditions.
Who might not be able to take colchicine?
Colchicine may not be suitable if you:
- Have severe kidney or liver disease
- Have a blood disorder
- Are taking certain medications that interact with colchicine (such as some antibiotics or statins)
Can I take colchicine if I’m pregnant or breastfeeding?
Colchicine isn’t usually recommended during pregnancy or breastfeeding. Speak to your doctor about alternative treatments.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is colchicine?
Colchicine is highly effective at reducing inflammation during a gout attack, but it works best when taken at the first sign of symptoms.
What should I do if I take too much?
Taking too much colchicine can be dangerous, leading to severe diarrhoea, vomiting, and organ damage. If you think you’ve taken too much, seek emergency medical help immediately.
What dose of colchicine is usually taken?
- For gout attacks: 1mg (two tablets) at the first sign of an attack, followed by 0.5mg one hour later
- For gout prevention: 0.5mg to 1mg once or twice daily
Your doctor will determine the correct dose based on your condition.
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What are the side effects of colchicine?
Common side effects include:
- Diarrhoea or stomach pain
- Nausea or vomiting
- Loss of appetite
Serious side effects, such as muscle weakness, numbness, or severe stomach pain, require urgent medical attention.
How should I take colchicine?
Colchicine is taken as tablets, usually swallowed whole with water.
When should colchicine be taken?
Colchicine should be taken as soon as gout symptoms appear, or daily as prescribed for prevention.
What are the brand names for colchicine?
Colchicine is available as a generic medicine, but some branded versions include:
- Colcrys
- Mitigare
Final thoughts
Colchicine is an effective treatment for gout and inflammation, but it should be taken exactly as prescribed to avoid serious side effects. If symptoms persist or side effects occur, speak to your doctor or pharmacist.
