Propylthiouracil

Propylthiouracil (PTU) is a medication used to treat hyperthyroidism (an overactive thyroid gland). It helps regulate thyroid hormone levels, relieving symptoms associated with this condition. If you’ve been prescribed propylthiouracil, here’s what you need to know.

What is propylthiouracil?

Propylthiouracil belongs to a group of medicines called antithyroid medications, which reduce the production of thyroid hormones.

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How does propylthiouracil work?

Propylthiouracil works by blocking the production of thyroid hormones, helping to bring hormone levels back to normal and relieve symptoms of hyperthyroidism.

What is propylthiouracil used to treat?

Propylthiouracil is commonly prescribed for:

  • Hyperthyroidism (overactive thyroid)
  • Graves’ disease
  • Preparing the thyroid gland for surgery or radioactive iodine therapy

Who can take propylthiouracil?

Propylthiouracil is usually suitable for adults and children, but dosage and treatment duration depend on the specific condition and individual factors. Always follow your doctor’s instructions carefully.

Who might not be able to take propylthiouracil?

Propylthiouracil may not be suitable if you:

  • Have a history of liver problems
  • Have had severe blood disorders or bone marrow issues
  • Are allergic to propylthiouracil or similar medicines

Can I take propylthiouracil if I’m pregnant or breastfeeding?

Propylthiouracil can sometimes be used during pregnancy, especially during the first trimester, under careful medical supervision. If you’re breastfeeding, speak to your doctor, as it can pass into breast milk.

What if I miss a dose?

If you forget a dose, take it as soon as you remember. If it’s nearly time for your next dose, skip the missed one—do not take two doses at once.

How effective is propylthiouracil?

When used as prescribed, propylthiouracil is highly effective at controlling symptoms of hyperthyroidism and restoring normal thyroid function.

What should I do if I take too much?

Taking too much propylthiouracil can cause nausea, vomiting, dizziness, or severe side effects affecting your liver or blood cells. If you think you’ve taken too much, seek medical help immediately.

What dose of propylthiouracil is usually taken?

  • Adults: Typically 100–200mg, taken two to three times daily
  • Children: Dose based on age and weight, supervised closely by a doctor

Always follow your doctor’s specific dosing instructions.

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What are the side effects of propylthiouracil?

Common side effects include:

  • Mild nausea or upset stomach
  • Rash or itching
  • Headache
  • Dizziness

Serious side effects requiring immediate medical attention include:

  • Signs of liver problems (jaundice, dark urine)
  • Severe sore throat, fever, or signs of infection (possible blood disorders)

How should I take propylthiouracil?

Propylthiouracil usually comes in tablet form and should be swallowed whole with water. Take it at regular intervals throughout the day as instructed.

When should propylthiouracil be taken?

Take propylthiouracil exactly as prescribed, usually two to three times daily at evenly spaced intervals to maintain stable hormone levels.

What are the brand names for propylthiouracil?

Propylthiouracil is generally available under its generic name, but brand names include:

  • PTU
  • Propyl-Thyracil

Final thoughts

Propylthiouracil is effective for managing hyperthyroidism and associated conditions. Always follow your doctor’s advice carefully, and seek medical attention if you experience side effects or have any concerns.

Always consult a medical professional
This article is for informational purposes only and is not a substitute for medical advice. Always consult a healthcare professional before starting, stopping or changing any medication. If you have concerns about your medication or experience side effects, speak to your doctor or pharmacist immediately.

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