Co-Beneldopa

Co-beneldopa is a medication used to treat Parkinson’s disease and Parkinsonism. It helps improve movement, reduce stiffness, and manage symptoms by increasing dopamine levels in the brain. If you’ve been prescribed co-beneldopa, here’s what you need to know.

What is co-beneldopa?

Co-beneldopa is a combination medication that contains levodopa (a precursor to dopamine) and benserazide (which helps levodopa work more effectively in the brain).

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How does co-beneldopa work?

Levodopa is converted into dopamine in the brain, helping to improve movement and reduce Parkinson’s symptoms.

Benserazide prevents levodopa from breaking down before it reaches the brain, making it more effective and reducing side effects.

What is co-beneldopa used to treat?

Co-beneldopa is commonly prescribed for:

  • Parkinson’s disease (to improve movement and reduce stiffness, tremors, and slowness)
  • Parkinsonism (symptoms similar to Parkinson’s caused by other conditions or medications)

Who can take co-beneldopa?

Co-beneldopa is suitable for most adults with Parkinson’s disease, as prescribed by a doctor.

Who might not be able to take co-beneldopa?

Co-beneldopa may not be suitable if you:

  • Have severe kidney or liver disease
  • Have a history of severe psychiatric conditions (such as psychosis)
  • Have narrow-angle glaucoma
  • Are taking certain antidepressants (such as MAOIs)

Can I take co-beneldopa if I’m pregnant or breastfeeding?

Co-beneldopa isn’t usually recommended during pregnancy or breastfeeding, but your doctor will assess the benefits and risks before prescribing it.

What if I miss a dose?

If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.

How effective is co-beneldopa?

Co-beneldopa is highly effective at improving movement and reducing symptoms of Parkinson’s disease when taken consistently.

What should I do if I take too much?

Taking too much co-beneldopa can cause severe nausea, confusion, irregular heartbeat, or muscle stiffness. If you think you’ve taken too much, seek medical help immediately.

What dose of co-beneldopa is usually taken?

  • For Parkinson’s disease: Starting dose is usually 50mg/12.5mg three to four times daily, gradually increased as needed.
  • Maintenance dose: Varies depending on symptom control, up to 200mg/50mg per dose, taken multiple times daily.

Your doctor will determine the correct dose based on your condition.

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What are the side effects of co-beneldopa?

Common side effects include:

  • Nausea or vomiting
  • Dizziness or lightheadedness
  • Drowsiness or fatigue
  • Unusual dreams or hallucinations
  • Involuntary movements (dyskinesia)

Serious side effects, such as severe mood changes, confusion, or chest pain, require urgent medical attention.

How should I take co-beneldopa?

Co-beneldopa is taken as capsules or dispersible tablets, usually multiple times daily, with or without food.

When should co-beneldopa be taken?

Co-beneldopa should be taken at the same times each day, as prescribed by your doctor. Taking it with food may help reduce nausea, but avoid high-protein meals, as they may interfere with absorption.

What are the brand names for co-beneldopa?

Co-beneldopa is available as a generic medicine, but some branded versions include:

  • Madopar

Final thoughts

Co-beneldopa is an effective treatment for Parkinson’s disease, but it should be taken exactly as prescribed. Regular monitoring may be required to adjust the dose and manage side effects. If symptoms worsen or side effects occur, speak to your doctor or pharmacist.

Always consult a medical professional
This article is for informational purposes only and is not a substitute for medical advice. Always consult a healthcare professional before starting, stopping or changing any medication. If you have concerns about your medication or experience side effects, speak to your doctor or pharmacist immediately.

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