How does adalimumab work?
In autoimmune diseases, the immune system attacks healthy parts of the body, causing inflammation. Adalimumab blocks TNF-alpha, a protein involved in inflammation, helping to relieve symptoms and prevent further damage.
What is adalimumab used to treat?
Adalimumab is prescribed for several inflammatory conditions, including:
- Rheumatoid arthritis
- Psoriatic arthritis
- Ankylosing spondylitis
- Crohn’s disease
- Ulcerative colitis
- Plaque psoriasis
- Hidradenitis suppurativa (a chronic skin condition)
- Uveitis (eye inflammation)
Who can take adalimumab?
Adalimumab is usually prescribed to adults and children with inflammatory conditions when other treatments haven’t worked well enough.
Who might not be able to take adalimumab?
Adalimumab may not be suitable if you:
- Have an active infection
- Have tuberculosis (TB) or a history of TB
- Have multiple sclerosis (MS) or similar nervous system conditions
- Are allergic to adalimumab or any of its ingredients
- Are taking other immune-suppressing medicines (your doctor will assess if it’s safe)
Can I take adalimumab if I’m pregnant or breastfeeding?
Adalimumab is sometimes used during pregnancy if the benefits outweigh the risks. If you are pregnant, planning a pregnancy, or breastfeeding, speak to your doctor first.
What if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to your next scheduled dose, skip the missed one—don’t take two doses at once.
How effective is adalimumab?
Adalimumab is highly effective in reducing inflammation and preventing disease progression in conditions like arthritis and Crohn’s disease. It may take a few weeks to months to see the full benefits.
What should I do if I take too much adalimumab?
If you take too much adalimumab or use it incorrectly, contact a healthcare professional. Seek immediate medical attention if you experience serious side effects.
What dose of adalimumab is usually taken?
The usual dose for adults is 40mg every two weeks, given as an injection under the skin. Some conditions may require a different dosing schedule, which your doctor will advise you on.
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What are the side effects of adalimumab?
Common side effects include:
- Injection site reactions (redness, swelling, pain)
- Headaches
- Nausea
- Respiratory infections (e.g., colds, sinus infections)
More serious side effects include increased risk of infections, liver problems, and allergic reactions. Seek medical help if you experience:
- Fever, chills, or persistent infections
- Unexplained bruising or bleeding
- Severe dizziness or shortness of breath
How should I take adalimumab?
Adalimumab is given as an injection under the skin (subcutaneous injection). It comes in a pre-filled pen or syringe and can be self-administered after proper training.
When should adalimumab be taken?
Adalimumab is typically injected once every two weeks, but dosing schedules may vary depending on your condition. Your doctor will provide clear instructions on when to take it.
What are the brand names for adalimumab?
Adalimumab is available under the brand name Humira, as well as biosimilar versions, including:
- Amgevita
- Hulio
- Hyrimoz
- Imraldi
- Idacio
Final thoughts
Adalimumab is an effective treatment for many inflammatory conditions. It can help reduce pain, swelling, and long-term damage, but regular check-ups and monitoring are important. If you have any concerns about side effects or effectiveness, speak to your doctor or pharmacist.
