How does alendronic acid work?
Alendronic acid slows down the process of bone resorption, allowing bones to remain strong and less prone to fractures.
What is alendronic acid used to treat?
Alendronic acid is commonly prescribed for:
- Osteoporosis (to reduce the risk of fractures in postmenopausal women and men)
- Osteoporosis caused by long-term steroid use
- Paget’s disease of bone (a condition that causes abnormal bone growth)
Who can take alendronic acid?
Alendronic acid is suitable for most adults at risk of bone fractures, particularly postmenopausal women and people taking long-term corticosteroids.
Who might not be able to take alendronic acid?
Alendronic acid may not be suitable if you:
- Have severe kidney disease
- Have low calcium levels (hypocalcaemia)
- Have swallowing difficulties or oesophageal problems
- Are unable to sit or stand upright for at least 30 minutes after taking it
Can I take alendronic acid if I’m pregnant or breastfeeding?
Alendronic acid isn’t usually recommended during pregnancy or breastfeeding. Speak to your doctor about alternative treatments.
What if I miss a dose?
If taken once a week: Take it the next morning if you remember. If more than a day has passed, skip the missed dose and take your next scheduled dose—do not take two doses at once.
If taken daily: Skip the missed dose and take your next dose at the usual time.
How effective is alendronic acid?
Alendronic acid is highly effective at reducing the risk of fractures when taken correctly, but it may take several months to see full benefits.
What should I do if I take too much?
Taking too much alendronic acid can cause irritation or ulcers in the stomach and oesophagus. If you think you’ve taken too much, seek medical help immediately and avoid lying down.
What dose of alendronic acid is usually taken?
- For osteoporosis: 70mg once weekly or 10mg once daily
- For Paget’s disease: 40mg once daily for 6 months
Your doctor will determine the correct dose based on your condition.
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What are the side effects of alendronic acid?
Common side effects include:
- Heartburn or indigestion
- Nausea
- Bone, muscle, or joint pain
- Headache
Serious side effects, such as severe oesophageal irritation, jaw problems (osteonecrosis), or unusual thigh bone fractures, require urgent medical attention.
How should I take alendronic acid?
- Take it first thing in the morning, on an empty stomach.
- Swallow the tablet whole with a full glass of water.
- Stay upright (sitting or standing) for at least 30 minutes after taking it to prevent oesophageal irritation.
When should alendronic acid be taken?
Alendronic acid should be taken at the same time each week (if taking weekly) or each morning (if taking daily).
What are the brand names for alendronic acid?
Alendronic acid is available as a generic medicine, but some branded versions include:
- Fosamax
- Binosto (effervescent tablets)
Final thoughts
Alendronic acid is an effective treatment for osteoporosis and bone conditions, but it must be taken correctly to avoid stomach irritation. If you experience severe side effects or have difficulty taking it, speak to your doctor or pharmacist.
