How does anastrozole work?
Anastrozole blocks the enzyme aromatase, which converts androgens into oestrogen. This helps reduce the levels of oestrogen, slowing or stopping the growth of hormone-receptor-positive breast cancer cells.
What is anastrozole used to treat?
Anastrozole is commonly prescribed for:
- Early-stage breast cancer (to reduce the risk of recurrence after surgery)
- Advanced or metastatic breast cancer (to slow cancer progression)
- Preventing breast cancer recurrence in high-risk postmenopausal women
Who can take anastrozole?
Anastrozole is suitable for postmenopausal women with hormone-sensitive breast cancer, as prescribed by a doctor.
Who might not be able to take anastrozole?
Anastrozole may not be suitable if you:
- Have severe liver disease
- Have osteoporosis or a high risk of fractures
- Are still producing oestrogen (premenopausal women or pregnant women)
- Have a history of allergic reactions to anastrozole or similar medications
Can I take anastrozole if I’m pregnant or breastfeeding?
Anastrozole isn’t suitable during pregnancy or breastfeeding. If you are pregnant or planning to conceive, speak to your doctor about alternative treatments.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is anastrozole?
Anastrozole is highly effective at reducing oestrogen levels and slowing the growth of hormone-receptor-positive breast cancer.
What should I do if I take too much?
Taking too much anastrozole may increase the risk of side effects such as nausea, dizziness, or bone pain. If you think you’ve taken too much, seek medical advice immediately.
What dose of anastrozole is usually taken?
- For breast cancer treatment: 1mg once daily
Your doctor will determine the correct dose based on your condition.
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What are the side effects of anastrozole?
Common side effects include:
- Hot flushes
- Joint pain or stiffness
- Weakness or fatigue
- Osteoporosis (bone thinning)
- Nausea
Serious side effects, such as severe bone loss, liver problems, or allergic reactions, require urgent medical attention.
How should I take anastrozole?
Anastrozole is taken as tablets, usually once daily, with or without food.
When should anastrozole be taken?
Anastrozole should be taken at the same time each day, as prescribed by your doctor.
What are the brand names for anastrozole?
Anastrozole is available as a generic medicine, but some branded versions include:
- Arimidex
Final thoughts
Anastrozole is an effective treatment for hormone-sensitive breast cancer, but it should be taken exactly as prescribed. Regular monitoring may be needed to check bone health and side effects. If you experience side effects, speak to your doctor or pharmacist.
