How does buprenorphine work?
Buprenorphine binds to opioid receptors, reducing pain signals and alleviating withdrawal symptoms in people with opioid addiction.
What is buprenorphine used to treat?
Buprenorphine is commonly prescribed for:
- Moderate to severe pain (when other painkillers are not effective)
- Opioid dependence (as part of medication-assisted treatment to reduce withdrawal symptoms and cravings)
Who can take buprenorphine?
Buprenorphine is suitable for most adults with severe pain or opioid dependence, as prescribed by a doctor.
Who might not be able to take buprenorphine?
Buprenorphine may not be suitable if you:
- Have severe breathing problems (such as COPD or sleep apnoea)
- Have a history of opioid addiction but are not in a treatment program
- Have liver disease (your doctor may adjust your dose)
- Are taking other sedative medications (such as benzodiazepines)
Can I take buprenorphine if I’m pregnant or breastfeeding?
Buprenorphine may be used during pregnancy or breastfeeding, but only under medical supervision, as it can affect the baby.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is buprenorphine?
Buprenorphine is highly effective at managing pain and opioid dependence when taken as prescribed.
What should I do if I take too much?
Taking too much buprenorphine can cause slow breathing, extreme drowsiness, or unconsciousness. If you think you’ve taken too much, seek emergency medical help immediately.
What dose of buprenorphine is usually taken?
- For pain relief: 200mcg to 400mcg every 6 to 8 hours (or patches used once weekly)
- For opioid dependence: Starting dose of 2mg to 8mg daily, increasing as needed
Your doctor will determine the correct dose based on your condition.
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What are the side effects of buprenorphine?
Common side effects include:
- Drowsiness or dizziness
- Nausea or vomiting
- Constipation
- Headache
- Sweating
Serious side effects, such as breathing difficulties or allergic reactions, require urgent medical attention.
How should I take buprenorphine?
Buprenorphine is available as tablets, sublingual (under the tongue) films, patches, or injections. Follow your doctor’s instructions carefully.
When should buprenorphine be taken?
Buprenorphine should be taken at the same time each day, as prescribed.
What are the brand names for buprenorphine?
Buprenorphine is available as a generic medicine, but some branded versions include:
- Subutex (for opioid dependence)
- BuTrans (pain relief patches)
- Temgesic (for pain relief)
Final thoughts
Buprenorphine is an effective painkiller and opioid dependence treatment, but it should be taken exactly as prescribed due to the risk of dependence. If you experience unusual symptoms, speak to your doctor or pharmacist.
