How does chloramphenicol work?
Chloramphenicol blocks bacterial protein synthesis, stopping bacteria from multiplying and allowing the immune system to fight the infection.
What is chloramphenicol used to treat?
Chloramphenicol is commonly prescribed for:
- Eye infections (such as bacterial conjunctivitis)
- Ear infections
- Serious bacterial infections (such as meningitis and typhoid fever, in hospital settings)
Who can take chloramphenicol?
Chloramphenicol is suitable for most adults and children, but your doctor will determine if it’s right for you.
Who might not be able to take chloramphenicol?
Chloramphenicol may not be suitable if you:
- Have a history of blood disorders (such as aplastic anaemia)
- Have liver or kidney disease
- Have had an allergic reaction to chloramphenicol or similar antibiotics
- Are pregnant or breastfeeding (only used if necessary)
Can I take chloramphenicol if I’m pregnant or breastfeeding?
Chloramphenicol isn’t usually recommended during pregnancy or while breastfeeding, as it may pass to the baby. Speak to your doctor for alternative treatments.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is chloramphenicol?
Chloramphenicol is highly effective at treating bacterial infections when taken as prescribed.
What should I do if I take too much?
Taking too much chloramphenicol may cause serious side effects, including bone marrow suppression. If you think you’ve taken too much, seek medical help immediately.
What dose of chloramphenicol is usually taken?
- For eye infections: 1 drop every 2 hours for the first 48 hours, then every 4 hours
- For ear infections: 3 drops into the affected ear up to three times daily
- For serious bacterial infections: Given as an injection in hospital settings
Your doctor will determine the correct dose based on your infection.
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What are the side effects of chloramphenicol?
Common side effects include:
- Mild stinging or burning (for eye drops)
- Temporary blurred vision
- Skin irritation (for topical use)
Serious side effects, such as bone marrow suppression or severe allergic reactions, require urgent medical attention.
How should I take chloramphenicol?
Chloramphenicol is available as eye drops, ointment, ear drops, capsules, or injections. Follow your doctor’s instructions carefully.
When should chloramphenicol be taken?
Chloramphenicol should be taken at evenly spaced times throughout the day as prescribed.
What are the brand names for chloramphenicol?
Chloramphenicol is available as a generic medicine, but some branded versions include:
- Optrex Infected Eye Drops
- Chloromycetin
Final thoughts
Chloramphenicol is an effective antibiotic for bacterial infections, but it should only be used when necessary due to potential side effects. To get the best results, take it as prescribed and complete the full course. If you experience unusual symptoms, speak to your doctor or pharmacist.
