Clonidine

Clonidine is a medication used to treat high blood pressure (hypertension), migraines, and withdrawal symptoms. It works by relaxing blood vessels and calming overactive nerve signals. If you’ve been prescribed clonidine, here’s what you need to know.

What is clonidine?

Clonidine is a centrally acting alpha-agonist that lowers blood pressure and helps manage certain neurological and withdrawal symptoms.

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How does clonidine work?

Clonidine stimulates alpha receptors in the brain, reducing nerve signals that tighten blood vessels and slowing heart rate, which lowers blood pressure.

What is clonidine used to treat?

Clonidine is commonly prescribed for:

  • High blood pressure (hypertension)
  • Migraine prevention
  • Withdrawal symptoms from opioids or nicotine
  • ADHD (attention deficit hyperactivity disorder) (in some cases)
  • Menopausal hot flushes (as an alternative treatment)

Who can take clonidine?

Clonidine is suitable for most adults and children, depending on the condition being treated.

Who might not be able to take clonidine?

Clonidine may not be suitable if you:

  • Have low blood pressure (hypotension)
  • Have severe heart disease or an irregular heartbeat
  • Have a history of depression
  • Are taking other medications that lower blood pressure

Can I take clonidine if I’m pregnant or breastfeeding?

Clonidine isn’t usually recommended during pregnancy or breastfeeding unless advised by your doctor.

What if I miss a dose?

If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.

How effective is clonidine?

Clonidine is highly effective at lowering blood pressure and managing withdrawal symptoms when taken as prescribed.

What should I do if I take too much?

Taking too much clonidine can cause dangerously low blood pressure, slow heart rate, or severe drowsiness. If you think you’ve taken too much, seek emergency medical help immediately.

What dose of clonidine is usually taken?

  • For high blood pressure: 50mcg to 300mcg twice daily
  • For migraine prevention: 50mcg to 75mcg twice daily
  • For withdrawal symptoms: 100mcg to 400mcg daily, as prescribed

Your doctor will determine the correct dose based on your condition.

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What are the side effects of clonidine?

Common side effects include:

  • Drowsiness or dizziness
  • Dry mouth
  • Fatigue
  • Constipation
  • Low blood pressure when standing up (postural hypotension)

Serious side effects, such as severe drowsiness, confusion, or difficulty breathing, require urgent medical attention.

How should I take clonidine?

Clonidine is taken as tablets, patches, or liquid, usually once or twice daily.

When should clonidine be taken?

Clonidine should be taken at the same time each day, with or without food.

What are the brand names for clonidine?

Clonidine is available as a generic medicine, but some branded versions include:

  • Catapres
  • Dixarit (for migraines and menopausal symptoms)

Final thoughts

Clonidine is an effective treatment for high blood pressure, migraines, and withdrawal symptoms, but it must be taken exactly as prescribed. If you experience side effects, speak to your doctor or pharmacist.

Always consult a medical professional
This article is for informational purposes only and is not a substitute for medical advice. Always consult a healthcare professional before starting, stopping or changing any medication. If you have concerns about your medication or experience side effects, speak to your doctor or pharmacist immediately.

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