How does dabigatran work?
Dabigatran blocks thrombin, an enzyme needed for blood clotting. This helps prevent clots from forming in the blood vessels and reduces the risk of serious complications like stroke.
What is dabigatran used to treat?
Dabigatran is commonly prescribed for:
- Preventing stroke and blood clots in people with atrial fibrillation (AF)
- Treating and preventing deep vein thrombosis (DVT) and pulmonary embolism (PE)
- Preventing blood clots after hip or knee replacement surgery
Who can take dabigatran?
Dabigatran is suitable for most adults at risk of blood clots, as prescribed by a doctor.
Who might not be able to take dabigatran?
Dabigatran may not be suitable if you:
- Have active bleeding or a bleeding disorder
- Have severe kidney disease
- Have a history of stomach ulcers or gastrointestinal bleeding
- Are taking certain medications that interact with blood thinners
Can I take dabigatran if I’m pregnant or breastfeeding?
Dabigatran isn’t usually recommended during pregnancy or breastfeeding, as it may increase the risk of bleeding. Speak to your doctor about safer alternatives.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is dabigatran?
Dabigatran is highly effective at preventing stroke and blood clots when taken consistently as prescribed.
What should I do if I take too much?
Taking too much dabigatran can increase the risk of serious bleeding. If you experience unusual bruising, blood in your urine or stool, or unexplained bleeding, seek urgent medical attention.
What dose of dabigatran is usually taken?
- For atrial fibrillation: 150mg twice daily (or 110mg twice daily for certain patients)
- For DVT and PE treatment: 150mg twice daily after initial treatment with an injectable anticoagulant
- For clot prevention after surgery: 110mg to 220mg once daily
Your doctor will determine the correct dose based on your condition.
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What are the side effects of dabigatran?
Common side effects include:
- Increased risk of bleeding (nosebleeds, easy bruising)
- Stomach pain or indigestion
- Nausea
- Tiredness
Serious side effects, such as severe bleeding, black stools, or coughing up blood, require urgent medical attention.
How should I take dabigatran?
Dabigatran is taken as capsules, usually twice daily, with or without food. Swallow the capsules whole with water—do not crush or chew them.
When should dabigatran be taken?
Dabigatran should be taken at the same times each day, as prescribed by your doctor.
What are the brand names for dabigatran?
Dabigatran is available under the brand name:
- Pradaxa
Final thoughts
Dabigatran is an effective anticoagulant that reduces the risk of stroke and blood clots, but it should be taken exactly as prescribed. Regular monitoring may be needed to check for bleeding risks. If side effects occur, speak to your doctor or pharmacist.
