How does dapagliflozin work?
Dapagliflozin lowers blood sugar by blocking the reabsorption of glucose in the kidneys, allowing excess sugar to be excreted in urine. It also reduces excess fluid in the body, which can help with heart failure and kidney disease.
What is dapagliflozin used to treat?
Dapagliflozin is prescribed for:
- Type 2 diabetes (to lower blood sugar levels)
- Heart failure (to reduce symptoms and hospitalisations)
- Chronic kidney disease (to protect kidney function and lower the risk of complications)
Who can take dapagliflozin?
Dapagliflozin is suitable for adults with type 2 diabetes, heart failure, or chronic kidney disease, as prescribed by a doctor.
Who might not be able to take dapagliflozin?
Dapagliflozin may not be suitable if you:
- Have type 1 diabetes (risk of serious complications)
- Have severe kidney disease or are on dialysis
- Have low blood pressure or dehydration issues
- Have a history of frequent urinary tract infections
Can I take dapagliflozin if I’m pregnant or breastfeeding?
Dapagliflozin isn’t recommended during pregnancy or breastfeeding, as its effects on the baby are not well studied. If you are pregnant or planning to conceive, speak to your doctor about alternative treatments.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s nearly time for your next dose, skip the missed one—do not take two doses at once.
How effective is dapagliflozin?
Dapagliflozin is highly effective at lowering blood sugar levels, reducing hospitalisation rates in heart failure, and protecting kidney function in chronic kidney disease.
What should I do if I take too much?
Taking too much dapagliflozin may lead to low blood sugar (hypoglycaemia), dehydration, or serious infections. If you feel unwell, seek medical help immediately.
What dose of dapagliflozin is usually taken?
- For type 2 diabetes: 10mg once daily
- For heart failure and kidney disease: 10mg once daily
Your doctor will advise on the correct dose based on your condition.
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What are the side effects of dapagliflozin?
Common side effects include:
- Increased urination
- Urinary tract infections (UTIs)
- Genital infections (thrush)
- Dizziness or dehydration
Serious side effects, such as diabetic ketoacidosis (DKA) (a rare but life-threatening condition), require urgent medical attention.
How should I take dapagliflozin?
Dapagliflozin is taken as a tablet, once daily, usually in the morning, with or without food.
When should dapagliflozin be taken?
It’s best to take dapagliflozin at the same time each day, preferably in the morning.
What are the brand names for dapagliflozin?
Dapagliflozin is available under the brand name Forxiga in the UK.
Final thoughts
Dapagliflozin is an effective medication for managing type 2 diabetes, heart failure, and kidney disease. To get the best results, take it as prescribed, drink plenty of water, and monitor for side effects. If you have concerns, speak to your doctor or pharmacist.
