How does domperidone work?
Domperidone blocks dopamine receptors in the gut, speeding up the movement of food through the stomach and preventing nausea and vomiting.
What is domperidone used to treat?
Domperidone is commonly prescribed for:
- Nausea and vomiting (including after surgery or chemotherapy)
- Delayed stomach emptying (gastroparesis)
- Reflux-related symptoms (to improve digestion and reduce bloating)
Who can take domperidone?
Domperidone is suitable for most adults and children over 12 years old, depending on the condition being treated.
Who might not be able to take domperidone?
Domperidone may not be suitable if you:
- Have heart disease or an irregular heartbeat (QT prolongation)
- Have severe liver disease
- Have a blockage in your stomach or intestines
- Are taking certain medications that affect heart rhythm
Can I take domperidone if I’m pregnant or breastfeeding?
Domperidone isn’t usually recommended during pregnancy or breastfeeding, but your doctor may prescribe it if the benefits outweigh the risks.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is domperidone?
Domperidone is highly effective at relieving nausea and improving digestion when taken as prescribed.
What should I do if I take too much?
Taking too much domperidone can cause dizziness, irregular heartbeat, or fainting. If you think you’ve taken too much, seek medical help immediately.
What dose of domperidone is usually taken?
- For nausea and vomiting: 10mg up to three times daily (maximum 30mg per day)
- For digestive problems: 10mg up to three times daily before meals
Your doctor will determine the correct dose based on your condition.
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What are the side effects of domperidone?
Common side effects include:
- Dry mouth
- Headache
- Dizziness
- Stomach cramps
Serious side effects, such as irregular heartbeat or severe dizziness, require urgent medical attention.
How should I take domperidone?
Domperidone is taken as tablets or liquid, usually before meals.
When should domperidone be taken?
Domperidone should be taken before meals, as food can delay its absorption.
What are the brand names for domperidone?
Domperidone is available as a generic medicine, but some branded versions include:
- Motilium
Final thoughts
Domperidone is an effective medication for nausea and digestive issues, but it should be taken exactly as prescribed due to the risk of heart-related side effects. If you experience unusual symptoms, speak to your doctor or pharmacist.