Domperidone

Domperidone is a medication used to relieve nausea, vomiting, and symptoms of slow digestion. It works by increasing the movement of food through the stomach and intestines, helping to reduce discomfort. If you’ve been prescribed domperidone, here’s what you need to know.

What is domperidone?

Domperidone is a prokinetic and anti-sickness (anti-emetic) medication that helps improve digestion and reduce nausea.

Find your prescription medicine

Sign up in seconds to easily manage your prescription medicine and we’ll even remind you when it’s time to take or reorder it!

How does domperidone work?

Domperidone blocks dopamine receptors in the gut, speeding up the movement of food through the stomach and preventing nausea and vomiting.

What is domperidone used to treat?

Domperidone is commonly prescribed for:

  • Nausea and vomiting (including after surgery or chemotherapy)
  • Delayed stomach emptying (gastroparesis)
  • Reflux-related symptoms (to improve digestion and reduce bloating)

Who can take domperidone?

Domperidone is suitable for most adults and children over 12 years old, depending on the condition being treated.

Who might not be able to take domperidone?

Domperidone may not be suitable if you:

  • Have heart disease or an irregular heartbeat (QT prolongation)
  • Have severe liver disease
  • Have a blockage in your stomach or intestines
  • Are taking certain medications that affect heart rhythm

Can I take domperidone if I’m pregnant or breastfeeding?

Domperidone isn’t usually recommended during pregnancy or breastfeeding, but your doctor may prescribe it if the benefits outweigh the risks.

What if I miss a dose?

If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.

How effective is domperidone?

Domperidone is highly effective at relieving nausea and improving digestion when taken as prescribed.

What should I do if I take too much?

Taking too much domperidone can cause dizziness, irregular heartbeat, or fainting. If you think you’ve taken too much, seek medical help immediately.

What dose of domperidone is usually taken?

  • For nausea and vomiting: 10mg up to three times daily (maximum 30mg per day)
  • For digestive problems: 10mg up to three times daily before meals

Your doctor will determine the correct dose based on your condition.

Powered by pharmacies

With over 1,700 pharmacy partners across the UK, you can get the help you need, wherever you are based.

Our website and mobile app make it easy and convenient to manage your health needs and book services at a pharmacy nearby.

What are the side effects of domperidone?

Common side effects include:

  • Dry mouth
  • Headache
  • Dizziness
  • Stomach cramps

Serious side effects, such as irregular heartbeat or severe dizziness, require urgent medical attention.

How should I take domperidone?

Domperidone is taken as tablets or liquid, usually before meals.

When should domperidone be taken?

Domperidone should be taken before meals, as food can delay its absorption.

What are the brand names for domperidone?

Domperidone is available as a generic medicine, but some branded versions include:

  • Motilium

Final thoughts

Domperidone is an effective medication for nausea and digestive issues, but it should be taken exactly as prescribed due to the risk of heart-related side effects. If you experience unusual symptoms, speak to your doctor or pharmacist.

Always consult a medical professional
This article is for informational purposes only and is not a substitute for medical advice. Always consult a healthcare professional before starting, stopping or changing any medication. If you have concerns about your medication or experience side effects, speak to your doctor or pharmacist immediately.

Download the app

Order prescriptions, book services, explore treatments and more, from your phone

download the healthera app
QR code link: https://healthera.app.link/x3gHGaQ5Otb