How does dosulepin work?
Dosulepin blocks the reuptake of serotonin and noradrenaline, increasing their levels in the brain. This helps improve mood and reduce nerve-related pain.
What is dosulepin used to treat?
Dosulepin is commonly prescribed for:
- Depression (when other treatments have not worked)
- Nerve pain (neuropathic pain) (such as diabetic neuropathy or postherpetic neuralgia)
Who can take dosulepin?
Dosulepin is suitable for most adults, but it is only prescribed when other antidepressants have not been effective.
Who might not be able to take dosulepin?
Dosulepin may not be suitable if you:
- Have heart disease or an irregular heartbeat
- Have epilepsy or a history of seizures
- Have glaucoma
- Are taking other antidepressants, such as MAOIs
Can I take dosulepin if I’m pregnant or breastfeeding?
Dosulepin isn’t usually recommended during pregnancy or breastfeeding, but your doctor will assess the benefits and risks before prescribing it.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is dosulepin?
Dosulepin is effective at treating depression and nerve pain, but it is generally used when other medications have not worked due to its potential risks.
What should I do if I take too much?
Taking too much dosulepin can be very dangerous, leading to seizures, irregular heartbeat, and severe drowsiness. If you think you’ve taken too much, seek emergency medical help immediately.
What dose of dosulepin is usually taken?
- For depression: Starting dose of 75mg daily, increasing to 150mg if needed
- For nerve pain: 25mg to 75mg once daily (usually at night)
- Your doctor will determine the correct dose based on your condition.
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What are the side effects of dosulepin?
Common side effects include:
- Drowsiness or dizziness
- Dry mouth
- Constipation
- Blurred vision
- Weight gain
Serious side effects, such as severe mood changes, heart problems, or difficulty breathing, require urgent medical attention.
How should I take dosulepin?
Dosulepin is taken as tablets or capsules, usually once daily, preferably at bedtime due to its sedative effects.
When should dosulepin be taken?
Dosulepin should be taken at the same time each day, usually in the evening.
What are the brand names for dosulepin?
Dosulepin is available as a generic medicine, but some branded versions include:
- Prothiaden
Final thoughts
Dosulepin is an effective treatment for depression and nerve pain, but it should only be used when other treatments have not worked due to the risk of side effects. Regular monitoring may be needed, and any unusual symptoms should be reported to your doctor.
