How does edoxaban work?
Edoxaban blocks Factor Xa, a protein involved in blood clotting. This helps prevent harmful clots from forming in the blood vessels, reducing the risk of strokes and other complications.
What is edoxaban used to treat?
Edoxaban is commonly prescribed for:
- Preventing strokes and blood clots in people with atrial fibrillation (AF)
- Treating and preventing deep vein thrombosis (DVT)
- Treating and preventing pulmonary embolism (PE)
Who can take edoxaban?
Edoxaban is suitable for most adults at risk of blood clots or with existing clot-related conditions.
Who might not be able to take edoxaban?
Edoxaban may not be suitable if you:
- Have active bleeding or a bleeding disorder
- Have severe liver disease
- Have very high blood pressure that is not controlled
- Are taking other strong blood thinners (unless advised by your doctor)
Can I take edoxaban if I’m pregnant or breastfeeding?
Edoxaban isn’t usually recommended during pregnancy or while breastfeeding due to the risk of bleeding. Speak to your doctor about safer alternatives.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is edoxaban?
Edoxaban is highly effective at preventing blood clots and strokes when taken as prescribed.
What should I do if I take too much?
Taking too much edoxaban can increase the risk of serious bleeding. If you experience unusual bruising, blood in your urine or stool, or unexplained bleeding, seek urgent medical attention.
What dose of edoxaban is usually taken?
- For stroke prevention in atrial fibrillation: 60mg once daily (or 30mg once daily for those with kidney problems or low body weight)
- For DVT and PE treatment: 60mg once daily after initial treatment with an injectable anticoagulant
Your doctor will determine the correct dose for your condition.
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What are the side effects of edoxaban?
Common side effects include:
- Increased bruising
- Nosebleeds or gum bleeding
- Mild stomach upset
Serious side effects, such as severe bleeding or signs of internal bleeding (e.g., black stools or coughing up blood), require urgent medical attention.
How should I take edoxaban?
Edoxaban is taken as a tablet, once daily, with or without food.
When should edoxaban be taken?
Edoxaban should be taken at the same time each day to maintain steady blood levels.
What are the brand names for edoxaban?
Edoxaban is available under the brand name:
- Lixiana
Final thoughts
Edoxaban is an effective anticoagulant that reduces the risk of stroke and blood clots. To stay safe, take it exactly as prescribed, and contact your doctor if you experience unusual bleeding or other side effects.
