How does eplerenone work?
Eplerenone blocks aldosterone, a hormone that causes the body to retain salt and water. This helps lower blood pressure and reduce fluid build-up in heart failure patients.
What is eplerenone used to treat?
Eplerenone is commonly prescribed for:
- High blood pressure (hypertension)
- Heart failure (to reduce the risk of worsening symptoms and hospitalisation)
- Reducing fluid retention in people with heart conditions
Who can take eplerenone?
Eplerenone is suitable for most adults with high blood pressure or heart failure, as prescribed by a doctor.
Who might not be able to take eplerenone?
Eplerenone may not be suitable if you:
- Have severe kidney disease or high potassium levels
- Have severe liver disease
- Are taking other potassium-sparing diuretics or certain blood pressure medications
Can I take eplerenone if I’m pregnant or breastfeeding?
Eplerenone isn’t usually recommended during pregnancy or breastfeeding. Speak to your doctor about safer alternatives.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is eplerenone?
Eplerenone is highly effective at lowering blood pressure and managing heart failure when taken as prescribed.
What should I do if I take too much?
Taking too much eplerenone can cause dangerously high potassium levels, dizziness, or irregular heartbeat. If you think you’ve taken too much, seek medical help immediately.
What dose of eplerenone is usually taken?
- For high blood pressure: 25mg to 50mg once daily
- For heart failure: 25mg once daily, increasing to 50mg if tolerated
Your doctor will determine the correct dose based on your condition.
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What are the side effects of eplerenone?
Common side effects include:
- Dizziness or lightheadedness
- Increased potassium levels (which may cause muscle weakness or irregular heartbeat)
- Tiredness
- Diarrhoea
Serious side effects, such as severe kidney problems or irregular heartbeat, require urgent medical attention.
How should I take eplerenone?
Eplerenone is taken as a tablet, once daily, swallowed whole with water.
When should eplerenone be taken?
Eplerenone can be taken at any time of day, but it’s best to take it at the same time each day.
What are the brand names for eplerenone?
Eplerenone is available as a generic medicine, but some branded versions include:
- Inspra
Final thoughts
Eplerenone is an effective medication for high blood pressure and heart failure, but it should be taken exactly as prescribed. Regular blood tests may be needed to monitor potassium levels. If you experience side effects, speak to your doctor or pharmacist.
