Hydroxocobalamin

Hydroxocobalamin is a form of vitamin B12 used to treat and prevent vitamin B12 deficiency. It plays a crucial role in red blood cell production, nerve function, and DNA synthesis. If you’ve been prescribed hydroxocobalamin, here’s what you need to know.

What is hydroxocobalamin?

Hydroxocobalamin is an injectable form of vitamin B12 that helps maintain healthy nerves, blood cells, and metabolism.

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How does hydroxocobalamin work?

Hydroxocobalamin helps the body absorb and use vitamin B12, which is essential for producing red blood cells and preventing nerve damage.

What is hydroxocobalamin used to treat?

Hydroxocobalamin is commonly prescribed for:

  • Vitamin B12 deficiency (caused by poor diet, pernicious anaemia, or absorption problems)
  • Pernicious anaemia (a condition where the body cannot absorb vitamin B12 properly)
  • Supporting nerve health (in conditions such as neuropathy)
  • Cyanide poisoning (in emergency cases)

Who can take hydroxocobalamin?

Hydroxocobalamin is suitable for most adults and children who need vitamin B12 supplementation.

Who might not be able to take hydroxocobalamin?

Hydroxocobalamin may not be suitable if you:

  • Have a history of allergic reactions to vitamin B12 injections
  • Have low potassium levels (hypokalaemia)
  • Have a rare genetic disorder affecting B12 metabolism

Can I take hydroxocobalamin if I’m pregnant or breastfeeding?

Yes, hydroxocobalamin is safe during pregnancy and breastfeeding, and it is often recommended to prevent deficiency.

What if I miss a dose?

If you miss a scheduled injection, take it as soon as possible. If it’s close to your next dose, skip the missed one—do not take extra doses to make up for it.

How effective is hydroxocobalamin?

Hydroxocobalamin is highly effective at raising vitamin B12 levels and preventing deficiency-related symptoms.

What should I do if I take too much?

Taking too much hydroxocobalamin is unlikely to cause harm, as excess amounts are usually excreted in urine. However, if you feel unwell, seek medical advice.

What dose of hydroxocobalamin is usually taken?

  • For vitamin B12 deficiency: 1mg injection every 2–3 months (or more frequently if needed)
  • For pernicious anaemia: 1mg injection every 2 months
  • For cyanide poisoning: Higher doses given in a hospital setting

Your doctor will determine the correct dose based on your condition.

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What are the side effects of hydroxocobalamin?

Common side effects include:

  • Mild pain or redness at the injection site
  • Nausea or diarrhoea
  • Headache
  • Skin rash or itching

Serious side effects, such as severe allergic reactions or breathlessness, require urgent medical attention.

How should I take hydroxocobalamin?

Hydroxocobalamin is administered as an injection into a muscle (intramuscular injection), usually by a healthcare professional.

When should hydroxocobalamin be taken?

Hydroxocobalamin injections are typically given every 2 to 3 months, as prescribed by a doctor.

What are the brand names for hydroxocobalamin?

Hydroxocobalamin is available as a generic medicine, but some branded versions include:

  • Cyanokit (for cyanide poisoning)
  • Neo-Cytamen

Final thoughts

Hydroxocobalamin is an effective treatment for vitamin B12 deficiency and pernicious anaemia, but it should be taken exactly as prescribed. If side effects occur, speak to your doctor or pharmacist.

Always consult a medical professional
This article is for informational purposes only and is not a substitute for medical advice. Always consult a healthcare professional before starting, stopping or changing any medication. If you have concerns about your medication or experience side effects, speak to your doctor or pharmacist immediately.

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