Isosorbide Mononitrate

Isosorbide mononitrate is a medication used to prevent angina (chest pain) in people with heart disease. It works by relaxing and widening blood vessels, improving blood flow to the heart. If you’ve been prescribed isosorbide mononitrate, here’s what you need to know.

What is isosorbide mononitrate?

Isosorbide mononitrate is a nitrate medication that helps prevent angina by improving blood flow to the heart muscle.

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How does isosorbide mononitrate work?

Isosorbide mononitrate relaxes and widens blood vessels, reducing the heart’s workload and helping prevent chest pain.

What is isosorbide mononitrate used to treat?

Isosorbide mononitrate is commonly prescribed for:

  • Preventing angina (chest pain)
  • Improving blood flow in people with coronary artery disease

Who can take isosorbide mononitrate?

Isosorbide mononitrate is suitable for most adults with heart-related conditions, as prescribed by a doctor.

Who might not be able to take isosorbide mononitrate?

Isosorbide mononitrate may not be suitable if you:

  • Have severe low blood pressure (hypotension)
  • Have a history of heart attack or stroke
  • Have anaemia (low red blood cell count)
  • Are taking medications for erectile dysfunction (such as sildenafil, tadalafil, or vardenafil)

Can I take isosorbide mononitrate if I’m pregnant or breastfeeding?

Isosorbide mononitrate isn’t usually recommended during pregnancy or breastfeeding, but your doctor will assess the risks and benefits.

What if I miss a dose?

If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.

How effective is isosorbide mononitrate?

Isosorbide mononitrate is highly effective at preventing angina when taken consistently as prescribed.

What should I do if I take too much?

Taking too much isosorbide mononitrate can cause dangerously low blood pressure, dizziness, or fainting. If you think you’ve taken too much, seek emergency medical help immediately.

What dose of isosorbide mononitrate is usually taken?

  • For preventing angina: 20mg to 60mg once or twice daily
  • For extended-release tablets: 30mg to 120mg once daily

Your doctor will determine the correct dose based on your condition.

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What are the side effects of isosorbide mononitrate?

Common side effects include:

  • Headache (common in the first few days of treatment)
  • Dizziness or lightheadedness
  • Flushing (warmth in the face and neck)
  • Nausea

Serious side effects, such as severe dizziness, fainting, or allergic reactions, require urgent medical attention.

How should I take isosorbide mononitrate?

Isosorbide mononitrate is taken as tablets (standard or extended-release), usually once or twice daily. Swallow whole with water.

When should isosorbide mononitrate be taken?

Isosorbide mononitrate should be taken at the same time each day, usually in the morning.

What are the brand names for isosorbide mononitrate?

Isosorbide mononitrate is available as a generic medicine, but some branded versions include:

  • Imdur
  • Monomax
  • Ismo

Final thoughts

Isosorbide mononitrate is an effective medication for preventing angina, but it should be taken exactly as prescribed. If side effects occur, speak to your doctor or pharmacist.

Always consult a medical professional
This article is for informational purposes only and is not a substitute for medical advice. Always consult a healthcare professional before starting, stopping or changing any medication. If you have concerns about your medication or experience side effects, speak to your doctor or pharmacist immediately.

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