How does isotretinoin work?
Isotretinoin shrinks the oil glands in the skin, reducing sebum (oil) production, which helps prevent acne formation. It also reduces inflammation and helps unclog pores.
What is isotretinoin used to treat?
Isotretinoin is commonly prescribed for:
- Severe acne (nodular or cystic acne)
- Acne that hasn’t improved with antibiotics or other treatments
- Acne that causes scarring
Who can take isotretinoin?
Isotretinoin is suitable for most adults and teenagers with severe acne, as prescribed by a dermatologist.
Who might not be able to take isotretinoin?
Isotretinoin may not be suitable if you:
- Are pregnant or trying to conceive (it can cause serious birth defects)
- Have liver disease
- Have high cholesterol or triglycerides
- Have a history of depression or mood disorders
Can I take isotretinoin if I’m pregnant or breastfeeding?
Isotretinoin must not be taken during pregnancy, as it can cause serious birth defects. Women taking isotretinoin must use effective contraception and undergo regular pregnancy tests. It is also not recommended while breastfeeding.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is isotretinoin?
Isotretinoin is highly effective, with most people seeing significant improvement in acne within 4 to 6 months of treatment.
What should I do if I take too much?
Taking too much isotretinoin can cause severe headaches, dizziness, nausea, and skin peeling. If you think you’ve taken too much, seek medical help immediately.
What dose of isotretinoin is usually taken?
- For acne: 0.5mg to 1mg per kg of body weight daily, taken for 16 to 24 weeks
Your doctor will determine the correct dose based on your weight and severity of acne.
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What are the side effects of isotretinoin?
Common side effects include:
- Dry skin, lips, and eyes
- Increased sensitivity to sunlight
- Nosebleeds
- Muscle and joint pain
Serious side effects, such as severe mood changes, vision problems, or liver issues, require urgent medical attention.
How should I take isotretinoin?
Isotretinoin is taken as capsules, usually once or twice daily with food to improve absorption.
When should isotretinoin be taken?
Isotretinoin should be taken at the same time each day, with food.
What are the brand names for isotretinoin?
Isotretinoin is available as a generic medicine, but some branded versions include:
- Roaccutane
- Accutane
- Isotretinoin (generic versions)
Final thoughts
Isotretinoin is an effective treatment for severe acne, but it comes with important safety precautions. To get the best results, follow your doctor’s instructions, use contraception if required, and report any side effects immediately.
