How does linagliptin work?
Linagliptin blocks the enzyme DPP-4, which increases levels of incretin hormones. These hormones help the pancreas release more insulin and reduce glucose production in the liver.
What is linagliptin used to treat?
Linagliptin is commonly prescribed for:
- Type 2 diabetes (to improve blood sugar control when diet and exercise alone are not enough)
- Combination therapy (often used with other diabetes medications such as metformin or insulin)
Who can take linagliptin?
Linagliptin is suitable for most adults with type 2 diabetes, as prescribed by a doctor.
Who might not be able to take linagliptin?
Linagliptin may not be suitable if you:
- Have type 1 diabetes (it is not effective for this type)
- Have a history of pancreatitis
- Have severe kidney disease (dose adjustment may be needed)
- Are taking other medications that affect blood sugar levels
Can I take linagliptin if I’m pregnant or breastfeeding?
Linagliptin isn’t usually recommended during pregnancy or breastfeeding. Speak to your doctor about safer alternatives.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is linagliptin?
Linagliptin is highly effective at lowering blood sugar levels when combined with a healthy diet and exercise.
What should I do if I take too much?
Taking too much linagliptin can cause low blood sugar (hypoglycaemia), especially when combined with other diabetes medications. If you experience symptoms like dizziness, sweating, or confusion, eat or drink something sugary and seek medical help if necessary.
What dose of linagliptin is usually taken?
- For type 2 diabetes: 5mg once daily
Your doctor will determine the correct dose based on your condition.
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What are the side effects of linagliptin?
Common side effects include:
- Headache
- Nausea or stomach discomfort
- Cold-like symptoms (blocked nose, sore throat)
- Joint or muscle pain
Serious side effects, such as pancreatitis, severe allergic reactions, or kidney problems, require urgent medical attention.
How should I take linagliptin?
Linagliptin is taken as tablets, usually once daily, with or without food.
When should linagliptin be taken?
Linagliptin should be taken at the same time each day, as prescribed by your doctor.
What are the brand names for linagliptin?
Linagliptin is available as a generic medicine, but some branded versions include:
- Trajenta
- Jentadueto (combined with metformin)
Final thoughts
Linagliptin is an effective medication for managing type 2 diabetes, but it should be taken exactly as prescribed. Regular monitoring of blood sugar levels is recommended. If side effects occur, speak to your doctor or pharmacist.
