How does medroxyprogesterone work?
Medroxyprogesterone mimics the effects of natural progesterone, helping regulate periods, prevent ovulation (in contraception), and maintain hormone balance in hormone therapy.
What is medroxyprogesterone used to treat?
Medroxyprogesterone is commonly prescribed for:
- Hormone replacement therapy (HRT) (to protect the uterus when taking oestrogen)
- Irregular or heavy periods (to help regulate the menstrual cycle)
- Endometriosis (to reduce pain and tissue growth)
- Contraception (as an injectable birth control method)
- Reducing the risk of uterine cancer (in women taking oestrogen for HRT)
Who can take medroxyprogesterone?
Medroxyprogesterone is suitable for most women, as prescribed by a doctor.
Who might not be able to take medroxyprogesterone?
Medroxyprogesterone may not be suitable if you:
- Have a history of blood clots or deep vein thrombosis (DVT)
- Have breast cancer or hormone-sensitive cancers
- Have unexplained vaginal bleeding
- Have liver disease
Can I take medroxyprogesterone if I’m pregnant or breastfeeding?
Medroxyprogesterone is not recommended during pregnancy but is sometimes used for contraception while breastfeeding. Speak to your doctor for advice.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is medroxyprogesterone?
Medroxyprogesterone is highly effective for regulating periods, supporting HRT, and preventing pregnancy when used as directed.
What should I do if I take too much?
Taking too much medroxyprogesterone may cause nausea, dizziness, or irregular bleeding. If you feel unwell, seek medical advice.
What dose of medroxyprogesterone is usually taken?
- For HRT and menstrual disorders: 2.5mg to 10mg daily for part of the cycle
- For contraception (Depo-Provera injection): 150mg every 12 weeks
Your doctor will determine the correct dose based on your condition.
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What are the side effects of medroxyprogesterone?
Common side effects include:
- Irregular periods or spotting
- Weight gain
- Headache
- Bloating or breast tenderness
Serious side effects, such as severe mood changes, blood clots, or allergic reactions, require urgent medical attention.
How should I take medroxyprogesterone?
Medroxyprogesterone is available as tablets or an injection. Follow your doctor’s instructions carefully.
When should medroxyprogesterone be taken?
Medroxyprogesterone should be taken at the same time each day, with or without food.
What are the brand names for medroxyprogesterone?
Medroxyprogesterone is available as a generic medicine, but some branded versions include:
- Provera (tablets)
- Depo-Provera (injection for contraception)
Final thoughts
Medroxyprogesterone is an effective treatment for menstrual disorders, hormone therapy, and contraception, but it should be taken exactly as prescribed. If side effects occur or symptoms persist, speak to your doctor or pharmacist.
