Memantine

Memantine is a medication used to treat moderate to severe Alzheimer’s disease. It helps improve memory, thinking, and daily function by regulating certain chemicals in the brain. If you’ve been prescribed memantine, here’s what you need to know.

What is memantine?

Memantine is an NMDA receptor antagonist that helps regulate brain activity and slow cognitive decline in Alzheimer’s disease.

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How does memantine work?

Memantine blocks excessive activity of glutamate, a brain chemical that can contribute to nerve cell damage in Alzheimer’s disease. This helps slow memory loss and cognitive decline.

What is memantine used to treat?

Memantine is commonly prescribed for:

  • Moderate to severe Alzheimer’s disease (to help with memory and daily activities)
  • Other forms of dementia (in some cases, as advised by a doctor)

Who can take memantine?

Memantine is suitable for most adults with moderate to severe Alzheimer’s disease.

Who might not be able to take memantine?

Memantine may not be suitable if you:

  • Have severe kidney disease
  • Have a history of seizures or epilepsy
  • Have uncontrolled high blood pressure
  • Are taking other medications that affect brain function

Can I take memantine if I’m pregnant or breastfeeding?

Memantine isn’t usually recommended during pregnancy or breastfeeding, as its effects on unborn babies and infants are not well studied.

What if I miss a dose?

If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.

How effective is memantine?

Memantine does not cure Alzheimer’s disease, but it can help slow cognitive decline and improve daily function.

What should I do if I take too much?

Taking too much memantine can cause confusion, dizziness, agitation, or hallucinations. If you think you’ve taken too much, seek emergency medical help immediately.

What dose of memantine is usually taken?

  • Starting dose: 5mg once daily
  • Maintenance dose: 10mg to 20mg once daily

Your doctor will determine the correct dose based on your condition.

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What are the side effects of memantine?

Common side effects include:

  • Dizziness or drowsiness
  • Headache
  • Constipation
  • Confusion or agitation

Serious side effects, such as severe mood changes, hallucinations, or seizures, require urgent medical attention.

How should I take memantine?

Memantine is taken as tablets, oral solution, or dispersible tablets, usually once daily.

When should memantine be taken?

Memantine should be taken at the same time each day, with or without food.

What are the brand names for memantine?

Memantine is available as a generic medicine, but some branded versions include:

  • Ebixa
  • Namenda

Final thoughts

Memantine is an effective treatment for slowing cognitive decline in Alzheimer’s disease, but it should be taken exactly as prescribed. If side effects occur or symptoms worsen, speak to your doctor or pharmacist.

Always consult a medical professional
This article is for informational purposes only and is not a substitute for medical advice. Always consult a healthcare professional before starting, stopping or changing any medication. If you have concerns about your medication or experience side effects, speak to your doctor or pharmacist immediately.

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