How does metoclopramide work?
Metoclopramide blocks dopamine receptors in the brain, helping to reduce nausea and vomiting. It also stimulates stomach and bowel movement, aiding digestion.
What is metoclopramide used to treat?
Metoclopramide is commonly prescribed for:
- Nausea and vomiting (including after surgery, chemotherapy, or migraines)
- Indigestion and acid reflux (gastroesophageal reflux disease – GERD)
- Gastroparesis (delayed stomach emptying), especially in people with diabetes
- Preventing nausea caused by radiation therapy
Who can take metoclopramide?
Metoclopramide is suitable for most adults and children over 1 year old, depending on the condition being treated.
Who might not be able to take metoclopramide?
Metoclopramide may not be suitable if you:
- Have a history of seizures or epilepsy
- Have Parkinson’s disease
- Have a bowel obstruction or stomach bleeding
- Have a history of movement disorders (such as tardive dyskinesia)
- Are taking certain antidepressants or antipsychotics
Can I take metoclopramide if I’m pregnant or breastfeeding?
Metoclopramide is sometimes prescribed during pregnancy to manage severe nausea and vomiting. If you are breastfeeding, speak to your doctor before taking it.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is metoclopramide?
Metoclopramide is highly effective at relieving nausea, vomiting, and stomach discomfort when taken as prescribed.
What should I do if I take too much?
Taking too much metoclopramide can cause severe drowsiness, muscle spasms, tremors, or restlessness. If you think you’ve taken too much, seek medical help immediately.
What dose of metoclopramide is usually taken?
- For nausea and vomiting: 10mg up to three times daily
- For gastroparesis and digestion issues: 10mg before meals
- For migraines (with painkillers): 10mg as a single dose
Your doctor will determine the correct dose based on your condition.
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What are the side effects of metoclopramide?
Common side effects include:
- Drowsiness or fatigue
- Diarrhoea
- Restlessness
- Headache
Serious side effects, such as involuntary muscle movements (tardive dyskinesia) or severe mood changes, require urgent medical attention.
How should I take metoclopramide?
Metoclopramide is taken as tablets, liquid, or injections. Tablets should be swallowed whole with water.
When should metoclopramide be taken?
It is usually taken 30 minutes before meals and before bedtime, if needed. Try to space doses evenly throughout the day, and do not exceed the maximum recommended dose.
What are the brand names for metoclopramide?
Metoclopramide is most often prescribed by its generic name, but branded versions may include:
- Maxolon
- Pramin (less commonly used in the UK)
Final thoughts
Metoclopramide is an effective treatment for nausea, vomiting, and digestive issues, especially when other options haven’t worked. It’s usually used for short periods due to the risk of side effects. Always follow your doctor’s advice and speak to a healthcare professional if you have any concerns while taking this medicine.
