Norethisterone

Norethisterone is a hormonal medicine used to treat a range of menstrual and reproductive health issues. It’s often prescribed to delay periods, manage heavy bleeding, or treat conditions like endometriosis. If you’ve been prescribed norethisterone, here’s what you need to know.

What is norethisterone?

Norethisterone is a synthetic form of progesterone, a hormone that plays a key role in regulating the menstrual cycle.

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How does norethisterone work?

Norethisterone mimics the effects of natural progesterone. It helps control the lining of the womb, which can delay periods, reduce heavy bleeding, and manage hormone-related symptoms.

What is norethisterone used to treat?

Norethisterone is commonly prescribed for:

  • Delaying periods (for travel, events, etc.)
  • Heavy or painful periods
  • Irregular periods
  • Endometriosis
  • Premenstrual syndrome (PMS)

Who can take norethisterone?

Most adult women and some teenagers can take norethisterone, but it should only be used under medical supervision.

Who might not be able to take norethisterone?

Norethisterone may not be suitable if you:

  • Are pregnant or think you may be
  • Have liver disease
  • Have or have had blood clots, stroke, or heart problems
  • Have unexplained vaginal bleeding
  • Have breast cancer or a history of it

Can I take norethisterone if I’m pregnant or breastfeeding?

Norethisterone should not be taken during pregnancy. If you’re breastfeeding, speak to your doctor—it may be prescribed with caution depending on your situation.

What if I miss a dose?

Take the missed dose as soon as you remember. If it’s nearly time for your next dose, skip the missed one—do not take two doses at once.

How effective is norethisterone?

Norethisterone is highly effective when used correctly to manage or delay periods and reduce hormonal symptoms.

What should I do if I take too much?

If you take too much norethisterone, you may feel sick, vomit, or experience spotting. Contact your doctor if you’re concerned or feel unwell.

What dose of norethisterone is usually taken?

To delay a period: 5mg three times a day, starting 3 days before your period is due

For heavy or painful periods: Dose and timing vary—follow your doctor’s instructions

For endometriosis or ongoing hormonal treatment: Dose and duration are tailored to your needs

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What are the side effects of norethisterone?

Common side effects include:

  • Bloating
  • Breast tenderness
  • Headache
  • Changes in mood
  • Spotting or breakthrough bleeding

Serious side effects (rare) include:

  • Blood clots (pain, swelling, or redness in the leg; sudden breathlessness)
  • Liver problems
  • Allergic reactions

Seek immediate medical help if you notice symptoms of a serious side effect.

How should I take norethisterone?

Take norethisterone tablets as prescribed, with water. Try to take them at the same times each day to keep hormone levels steady.

When should norethisterone be taken?

This depends on why you’re taking it. For period delay, start 3 days before your period is due and continue until you’re ready for your period to return. For other uses, your doctor will advise when and how long to take it.

What are the brand names for norethisterone?

Norethisterone is available as a generic medicine, but common brand names in the UK include:

Primolut N

Utovlan

Final thoughts

Norethisterone is a helpful and reliable treatment for managing periods and hormone-related conditions. Always use it as directed, and speak to your doctor or pharmacist if you experience side effects or have questions about your treatment.

Always consult a medical professional
This article is for informational purposes only and is not a substitute for medical advice. Always consult a healthcare professional before starting, stopping or changing any medication. If you have concerns about your medication or experience side effects, speak to your doctor or pharmacist immediately.

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