How does nortriptyline work?
Nortriptyline blocks the reabsorption of serotonin and noradrenaline, increasing their levels in the brain. This helps manage pain and improve mood.
What is nortriptyline used to treat?
Nortriptyline is commonly prescribed for:
- Nerve pain (neuropathy) (such as diabetic neuropathy or sciatica)
- Depression (in some cases)
- Migraine prevention
- Tension headaches
Who can take nortriptyline?
Nortriptyline is suitable for most adults, as prescribed by a doctor.
Who might not be able to take nortriptyline?
Nortriptyline may not be suitable if you:
- Have heart disease or an irregular heartbeat
- Have epilepsy or a history of seizures
- Have glaucoma
- Have bipolar disorder (without medical supervision)
- Are taking other antidepressants, such as MAOIs
Can I take nortriptyline if I’m pregnant or breastfeeding?
Nortriptyline isn’t usually recommended during pregnancy or breastfeeding, but your doctor will assess the risks and benefits.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is nortriptyline?
Nortriptyline is highly effective at treating nerve pain, migraines, and depression when taken consistently as prescribed.
What should I do if I take too much?
Taking too much nortriptyline can cause drowsiness, confusion, seizures, or irregular heartbeat. If you think you’ve taken too much, seek emergency medical help immediately.
What dose of nortriptyline is usually taken?
- For nerve pain and migraines: 10mg to 75mg once daily, usually at bedtime
- For depression: 25mg to 150mg daily, as prescribed
Your doctor will determine the correct dose based on your condition.
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What are the side effects of nortriptyline?
Common side effects include:
- Drowsiness or dizziness
- Dry mouth
- Constipation
- Weight gain
- Increased sweating
Serious side effects, such as severe mood changes, heart problems, or difficulty urinating, require urgent medical attention.
How should I take nortriptyline?
Nortriptyline is taken as tablets or capsules, usually once daily before bedtime.
When should nortriptyline be taken?
Nortriptyline should be taken at the same time each day, preferably in the evening to reduce drowsiness.
What are the brand names for nortriptyline?
Nortriptyline is available as a generic medicine, but some branded versions include:
- Pamelor
- Aventyl
Final thoughts
Nortriptyline is an effective treatment for nerve pain, migraines, and depression, but it should be taken exactly as prescribed. If side effects occur or symptoms persist, speak to your doctor or pharmacist.
