How does pioglitazone work?
Pioglitazone reduces insulin resistance, allowing the body to use insulin more effectively to lower blood sugar levels.
What is pioglitazone used to treat?
Pioglitazone is commonly prescribed for:
- Type 2 diabetes (to improve blood sugar control, often in combination with other diabetes medications)
Who can take pioglitazone?
Pioglitazone is suitable for most adults with type 2 diabetes, as prescribed by a doctor.
Who might not be able to take pioglitazone?
Pioglitazone may not be suitable if you:
- Have heart failure or a history of heart disease
- Have liver disease
- Have bladder cancer or a history of bladder problems
- Have osteoporosis or a high risk of fractures
Can I take pioglitazone if I’m pregnant or breastfeeding?
Pioglitazone isn’t usually recommended during pregnancy or breastfeeding. Speak to your doctor about safer alternatives.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is pioglitazone?
Pioglitazone is highly effective at lowering blood sugar levels when combined with a healthy diet and exercise.
What should I do if I take too much?
Taking too much pioglitazone can cause low blood sugar (hypoglycaemia), especially when combined with other diabetes medications. If you experience symptoms like dizziness, sweating, or confusion, eat or drink something sugary and seek medical help if necessary.
What dose of pioglitazone is usually taken?
- For type 2 diabetes: 15mg to 45mg once daily
Your doctor will determine the correct dose based on your condition.
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What are the side effects of pioglitazone?
Common side effects include:
- Weight gain
- Swelling in the legs or ankles (fluid retention)
- Bone fractures (especially in women)
- Increased risk of bladder infections
Serious side effects, such as heart failure, liver problems, or bladder cancer, require urgent medical attention.
How should I take pioglitazone?
Pioglitazone is taken as tablets, usually once daily, with or without food.
When should pioglitazone be taken?
Pioglitazone should be taken at the same time each day, as prescribed by your doctor.
What are the brand names for pioglitazone?
Pioglitazone is available as a generic medicine, but some branded versions include:
- Actos
- Competact (combined with metformin)
Final thoughts
Pioglitazone is an effective medication for managing type 2 diabetes, but it should be taken exactly as prescribed. Regular monitoring of blood sugar levels and possible side effects is recommended. If side effects occur, speak to your doctor or pharmacist.
