How does progesterone work?
Progesterone balances oestrogen levels and supports reproductive health by:
- Preparing the uterus for pregnancy
- Regulating the menstrual cycle
- Supporting early pregnancy development
- Protecting against excessive thickening of the uterine lining
What is progesterone used to treat?
Progesterone is commonly prescribed for:
- Hormone replacement therapy (HRT) (to relieve menopause symptoms and protect the uterus when taking oestrogen)
- Menstrual irregularities (such as heavy or irregular periods)
- Fertility treatments (to support implantation and early pregnancy)
- Preventing miscarriage (in some cases of recurrent pregnancy loss)
- Polycystic ovary syndrome (PCOS) (to regulate periods)
Who can take progesterone?
Progesterone is suitable for most women who need hormonal support for reproductive health or menopause management.
Who might not be able to take progesterone?
Progesterone may not be suitable if you:
- Have a history of blood clots or deep vein thrombosis (DVT)
- Have breast cancer or hormone-sensitive cancers
- Have unexplained vaginal bleeding
- Have liver disease
Can I take progesterone if I’m pregnant or breastfeeding?
Progesterone is often prescribed during pregnancy to support early development. It is usually safe while breastfeeding, but speak to your doctor before use.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is progesterone?
Progesterone is highly effective at regulating menstrual cycles, supporting pregnancy, and relieving menopause symptoms when taken as prescribed.
What should I do if I take too much?
Taking too much progesterone may cause nausea, dizziness, bloating, or mood changes. If you feel unwell, seek medical advice.
What dose of progesterone is usually taken?
- For HRT: 100mg to 200mg daily (with oestrogen therapy)
- For menstrual irregularities: 200mg for 10–12 days of the cycle
- For fertility support: 200mg to 400mg daily, as prescribed
Your doctor will determine the correct dose based on your condition.
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What are the side effects of progesterone?
Common side effects include:
- Drowsiness or dizziness
- Headache
- Bloating or breast tenderness
- Mood changes
Serious side effects, such as severe allergic reactions or blood clots, require urgent medical attention.
How should I take progesterone?
Progesterone is available as capsules, tablets, vaginal gels, suppositories, and injections. Follow your doctor’s instructions carefully.
When should progesterone be taken?
Progesterone is usually taken in the evening, as it can cause drowsiness.
What are the brand names for progesterone?
Progesterone is available as a generic medicine, but some branded versions include:
- Utrogestan
- Cyclogest
- Crinone
Final thoughts
Progesterone is an essential hormone for reproductive health, pregnancy support, and hormone therapy. To get the best results, take it as prescribed, and if side effects occur, speak to your doctor or pharmacist.
