How does risedronate work?
Risedronate slows down the process of bone resorption, allowing bones to remain strong and less prone to fractures.
What is risedronate used to treat?
Risedronate is commonly prescribed for:
- Osteoporosis (to reduce the risk of fractures in postmenopausal women and men)
- Osteoporosis caused by long-term steroid use
- Paget’s disease of bone (a condition that causes abnormal bone growth)
Who can take risedronate?
Risedronate is suitable for most adults at risk of bone fractures, particularly postmenopausal women and people taking long-term corticosteroids.
Who might not be able to take risedronate?
Risedronate may not be suitable if you:
- Have severe kidney disease
- Have low calcium levels (hypocalcaemia)
- Have swallowing difficulties or oesophageal problems
- Are unable to sit or stand upright for at least 30 minutes after taking it
Can I take risedronate if I’m pregnant or breastfeeding?
Risedronate isn’t usually recommended during pregnancy or breastfeeding. Speak to your doctor about safer alternatives.
What if I miss a dose?
- If taken once a week: Take it the next morning if you remember. If more than a day has passed, skip the missed dose and take your next scheduled dose—do not take two doses at once.
- If taken daily: Skip the missed dose and take your next dose at the usual time.
How effective is risedronate?
Risedronate is highly effective at reducing the risk of fractures when taken correctly, but it may take several months to see full benefits.
What should I do if I take too much?
Taking too much risedronate can cause irritation or ulcers in the stomach and oesophagus. If you think you’ve taken too much, seek medical help immediately and avoid lying down.
What dose of risedronate is usually taken?
- For osteoporosis: 35mg once weekly or 5mg once daily
- For Paget’s disease: 30mg once daily for 2 months
Your doctor will determine the correct dose based on your condition.
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What are the side effects of risedronate?
Common side effects include:
- Heartburn or indigestion
- Nausea
- Bone, muscle, or joint pain
- Headache
Serious side effects, such as severe oesophageal irritation, jaw problems (osteonecrosis), or unusual thigh bone fractures, require urgent medical attention.
How should I take risedronate?
- Take it first thing in the morning, on an empty stomach.
- Swallow the tablet whole with a full glass of water.
- Stay upright (sitting or standing) for at least 30 minutes after taking it to prevent oesophageal irritation.
When should risedronate be taken?
Risedronate should be taken at the same time each week (if taking weekly) or each morning (if taking daily).
What are the brand names for risedronate?
Risedronate is available as a generic medicine, but some branded versions include:
- Actonel
- Risedronate Sodium
Final thoughts
Risedronate is an effective treatment for osteoporosis and bone conditions, but it must be taken correctly to avoid stomach irritation. If you experience severe side effects or have difficulty taking it, speak to your doctor or pharmacist.
