Tibolone

Tibolone is a hormone replacement therapy (HRT) medication used to relieve menopause symptoms such as hot flushes, night sweats, and mood changes. It mimics the effects of oestrogen, progesterone, and testosterone in the body, helping maintain hormonal balance. If you’ve been prescribed tibolone, here’s what you need to know.

What is tibolone?

Tibolone is a synthetic hormone replacement therapy that acts like oestrogen, progesterone, and testosterone to help relieve menopause symptoms.

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How does tibolone work?

Tibolone replaces declining hormone levels in postmenopausal women, helping to reduce symptoms of menopause and protect bone health.

What is tibolone used to treat?

Tibolone is commonly prescribed for:

  • Relieving menopause symptoms (such as hot flushes, night sweats, and vaginal dryness)
  • Preventing osteoporosis (in postmenopausal women at risk of fractures)

Who can take tibolone?

Tibolone is suitable for postmenopausal women, as prescribed by a doctor.

Who might not be able to take tibolone?

Tibolone may not be suitable if you:

  • Have a history of breast cancer or hormone-sensitive cancers
  • Have a history of blood clots or stroke
  • Have unexplained vaginal bleeding
  • Have severe liver disease

Can I take tibolone if I’m pregnant or breastfeeding?

Tibolone isn’t suitable during pregnancy or breastfeeding, as it is intended for postmenopausal women only.

What if I miss a dose?

If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.

How effective is tibolone?

Tibolone is highly effective at reducing menopause symptoms and protecting bone health when taken as prescribed.

What should I do if I take too much?

Taking too much tibolone may cause nausea, dizziness, or irregular bleeding. If symptoms persist, seek medical advice.

What dose of tibolone is usually taken?

  • For menopause symptoms and osteoporosis prevention: 2.5mg once daily

Your doctor will determine the correct dose based on your health history.

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What are the side effects of tibolone?

Common side effects include:

  • Breast tenderness
  • Irregular vaginal bleeding or spotting
  • Headache
  • Weight gain
  • Mood changes

Serious side effects, such as blood clots, breast cancer risk, or stroke, require urgent medical attention.

How should I take tibolone?

Tibolone is taken as tablets, usually once daily, with or without food.

When should tibolone be taken?

Tibolone should be taken at the same time each day, as prescribed by your doctor.

What are the brand names for tibolone?

Tibolone is available as a generic medicine, but some branded versions include:

  • Livial

Final thoughts

Tibolone is an effective treatment for menopause symptoms and osteoporosis prevention, but it should be taken exactly as prescribed. Regular health check-ups are recommended. If side effects occur, speak to your doctor or pharmacist.

Always consult a medical professional
This article is for informational purposes only and is not a substitute for medical advice. Always consult a healthcare professional before starting, stopping or changing any medication. If you have concerns about your medication or experience side effects, speak to your doctor or pharmacist immediately.

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