How does ticagrelor work?
Ticagrelor blocks platelets from clumping together, reducing the risk of heart attacks, strokes, and complications in people with heart disease.
What is ticagrelor used to treat?
Ticagrelor is commonly prescribed for:
- Preventing heart attacks and strokes in people with heart disease
- Preventing complications after stent placement (percutaneous coronary intervention, PCI)
- Acute coronary syndrome (ACS) (such as unstable angina or a recent heart attack)
Who can take ticagrelor?
Ticagrelor is suitable for most adults at risk of cardiovascular events, as prescribed by a doctor.
Who might not be able to take ticagrelor?
Ticagrelor may not be suitable if you:
- Have active bleeding or a bleeding disorder
- Have a history of stroke due to bleeding in the brain
- Have severe liver disease
- Are taking certain blood thinners or strong CYP3A inhibitors
Can I take ticagrelor if I’m pregnant or breastfeeding?
Ticagrelor isn’t usually recommended during pregnancy or breastfeeding, as it may increase the risk of bleeding. Speak to your doctor about safer alternatives.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is ticagrelor?
Ticagrelor is highly effective at preventing blood clots and reducing the risk of heart attacks and strokes when taken consistently.
What should I do if I take too much?
Taking too much ticagrelor can increase the risk of serious bleeding. If you experience unusual bruising, blood in your urine or stool, or unexplained bleeding, seek urgent medical attention.
What dose of ticagrelor is usually taken?
- For preventing heart attacks and strokes: 90mg twice daily for 12 months, then 60mg twice daily if continued
- For acute coronary syndrome (ACS): Loading dose of 180mg, followed by 90mg twice daily
Your doctor will determine the correct dose based on your condition.
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What are the side effects of ticagrelor?
Common side effects include:
- Increased risk of bleeding (nosebleeds, easy bruising)
- Shortness of breath
- Dizziness or headache
- Nausea
Serious side effects, such as severe bleeding, black stools, or coughing up blood, require urgent medical attention.
How should I take ticagrelor?
Ticagrelor is taken as tablets, usually twice daily, with or without food.
When should ticagrelor be taken?
Ticagrelor should be taken at the same times each day, as prescribed by your doctor.
What are the brand names for ticagrelor?
Ticagrelor is available as a generic medicine, but some branded versions include:
- Brilique
- Brilinta (outside the UK)
Final thoughts
Ticagrelor is an effective medication for preventing heart attacks and strokes, but it should be taken exactly as prescribed. Regular monitoring may be needed to check for bleeding risks. If side effects occur, speak to your doctor or pharmacist.
