Varenicline

Varenicline is a medication used to help people stop smoking. It works by reducing cravings and withdrawal symptoms while also making smoking less pleasurable. If you’ve been prescribed varenicline, here’s what you need to know.

What is varenicline?

Varenicline is a smoking cessation aid that helps reduce nicotine cravings and withdrawal effects.

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How does varenicline work?

Varenicline targets nicotine receptors in the brain, reducing the pleasurable effects of smoking while easing withdrawal symptoms. This helps make quitting smoking easier.

What is varenicline used to treat?

Varenicline is commonly prescribed for:

  • Helping people stop smoking (as part of a structured quit plan)
  • Reducing nicotine cravings and withdrawal symptoms

Who can take varenicline?

Varenicline is suitable for most adults who want to quit smoking, as prescribed by a doctor.

Who might not be able to take varenicline?

Varenicline may not be suitable if you:

  • Have a history of mental health conditions, such as depression or anxiety
  • Have kidney disease (dose adjustments may be needed)
  • Are pregnant or breastfeeding
  • Have had previous serious side effects from varenicline

Can I take varenicline if I’m pregnant or breastfeeding?

Varenicline isn’t usually recommended during pregnancy or breastfeeding, as its effects on unborn babies and infants are not fully understood. Speak to your doctor about alternative treatments.

What if I miss a dose?

If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.

How effective is varenicline?

Varenicline is highly effective at helping people quit smoking when used alongside a structured quitting plan and behavioural support.

What should I do if I take too much?

Taking too much varenicline can cause nausea, dizziness, vomiting, or mood changes. If you think you’ve taken too much, seek medical advice immediately.

What dose of varenicline is usually taken?

  • Day 1 to 3: 0.5mg once daily
  • Day 4 to 7: 0.5mg twice daily
  • From Day 8 onwards: 1mg twice daily for 12 weeks

Your doctor will determine the correct dose based on your needs and treatment plan.

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What are the side effects of varenicline?

Common side effects include:

  • Nausea
  • Headache
  • Difficulty sleeping (insomnia or vivid dreams)
  • Dizziness

Serious side effects, such as mood changes, suicidal thoughts, or severe allergic reactions, require urgent medical attention.

How should I take varenicline?

Varenicline is taken as tablets, usually for 12 weeks, with or without food.

When should varenicline be taken?

Varenicline should be taken at the same time each day, usually in the morning and evening.

What are the brand names for varenicline?

Varenicline is available under the brand name:

  • Champix

Final thoughts

Varenicline is an effective treatment for quitting smoking, but it should be taken exactly as prescribed. Combining it with behavioural support can improve your chances of success. If side effects occur, speak to your doctor or pharmacist.

Always consult a medical professional
This article is for informational purposes only and is not a substitute for medical advice. Always consult a healthcare professional before starting, stopping or changing any medication. If you have concerns about your medication or experience side effects, speak to your doctor or pharmacist immediately.

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