How does quetiapine work?
Quetiapine affects dopamine and serotonin levels in the brain, helping to reduce symptoms of psychosis, stabilise mood, and improve overall mental well-being.
What is quetiapine used to treat?
Quetiapine is commonly prescribed for:
- Schizophrenia (to help with hallucinations, delusions, and disorganised thinking)
- Bipolar disorder (to manage manic and depressive episodes)
- Major depressive disorder (as an add-on treatment for some people with depression)
- Generalised anxiety disorder (occasionally prescribed off-label)
Who can take quetiapine?
Quetiapine is suitable for adults and some children over 12 years old, depending on the condition being treated.
Who might not be able to take quetiapine?
Quetiapine may not be suitable if you:
- Have heart disease or low blood pressure
- Have a history of seizures or epilepsy
- Have diabetes or high blood sugar
- Have liver disease
- Are taking certain antidepressants or other medications that affect heart rhythm
Can I take quetiapine if I’m pregnant or breastfeeding?
Quetiapine isn’t usually recommended during pregnancy or while breastfeeding unless the benefits outweigh the risks. Speak to your doctor if you are pregnant or planning to conceive.
What if I miss a dose?
If you forget to take a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is quetiapine?
Quetiapine is highly effective at treating symptoms of schizophrenia, bipolar disorder, and depression when taken as prescribed. It may take several weeks to notice full benefits.
What should I do if I take too much?
Taking too much quetiapine can be dangerous and may cause:
- Severe drowsiness
- Dizziness or fainting
- Irregular heartbeat
- Seizures
If you think you’ve taken too much, seek emergency medical help immediately.
What dose of quetiapine is usually taken?
- Schizophrenia & bipolar disorder: 150mg to 800mg daily, divided into doses
- Depression (as an add-on treatment): 50mg to 300mg once daily
Your doctor will decide the most suitable dose based on your condition and response to treatment.
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What are the side effects of quetiapine?
Common side effects include:
- Drowsiness or dizziness
- Weight gain
- Dry mouth
- Constipation
- Increased heart rate
Serious side effects, such as severe mood changes, uncontrollable movements, or signs of high blood sugar, require urgent medical attention.
How should I take quetiapine?
Quetiapine is taken as a tablet, swallowed whole with water. Some formulations should be taken on an empty stomach, while others can be taken with food—follow your doctor’s instructions.
When should quetiapine be taken?
Quetiapine is usually taken once or twice daily, depending on the condition being treated.
What are the brand names for quetiapine?
Quetiapine is available as a generic medicine, but some branded versions include:
- Seroquel
- Atrolak
Final thoughts
Quetiapine is an effective medication for managing schizophrenia, bipolar disorder, and depression. It should be taken exactly as prescribed, and any concerns about side effects should be discussed with a doctor or pharmacist.