How does clopidogrel work?
Clopidogrel blocks platelet aggregation, meaning it stops platelets in the blood from clumping together to form clots. This helps reduce the risk of heart attacks and strokes in people with certain heart and blood vessel conditions.
What is clopidogrel used to treat?
Clopidogrel is commonly prescribed for:
- Preventing heart attacks and strokes in people with heart disease
- Reducing the risk of clot formation after heart surgery or stent placement
- Peripheral arterial disease (PAD) (a condition affecting blood flow to the limbs)
- Preventing further clotting in people with previous strokes or mini-strokes (TIAs)
Who can take clopidogrel?
Clopidogrel is suitable for most adults at risk of blood clots.
Who might not be able to take clopidogrel?
Clopidogrel may not be suitable if you:
- Have a bleeding disorder or a history of stomach ulcers
- Have severe liver or kidney disease
- Are taking certain blood-thinning medications (like warfarin) unless advised by your doctor
- Have had an allergic reaction to clopidogrel or similar medicines
Can I take clopidogrel if I’m pregnant or breastfeeding?
Clopidogrel isn’t usually recommended during pregnancy or breastfeeding, but your doctor will assess if the benefits outweigh the risks.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is clopidogrel?
Clopidogrel is highly effective at preventing blood clots, but it must be taken regularly to work properly.
What should I do if I take too much?
Taking too much clopidogrel can increase the risk of serious bleeding. If you have unusual bruising, blood in your urine or stool, or unexplained bleeding, seek urgent medical attention.
What dose of clopidogrel is usually taken?
- For preventing heart attacks and strokes: 75mg once daily
- After a heart procedure (e.g., stent placement): A loading dose of 300mg, followed by 75mg daily
Your doctor will determine the correct dose for your condition.
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What are the side effects of clopidogrel?
Common side effects include:
- Increased bruising
- Nosebleeds or gum bleeding
- Diarrhoea or stomach discomfort
Serious side effects, such as severe bleeding, black stools, or jaundice (yellowing of the skin and eyes), require urgent medical attention.
How should I take clopidogrel?
Clopidogrel is taken as a tablet, once daily, with or without food.
When should clopidogrel be taken?
Clopidogrel should be taken at the same time each day to maintain steady blood levels.
What are the brand names for clopidogrel?
Clopidogrel is available as a generic medicine, but some branded versions include:
- Plavix
Final thoughts
Clopidogrel is an effective medication for preventing blood clots, but it should be taken consistently to work properly. If you experience unusual bleeding or side effects, speak to your doctor or pharmacist.
