How does lamotrigine work?
Lamotrigine reduces excessive electrical activity in the brain, helping to prevent seizures. It also stabilises mood swings in people with bipolar disorder by affecting neurotransmitters in the brain.
What is lamotrigine used to treat?
Lamotrigine is commonly prescribed for:
- Epilepsy (to prevent seizures in adults and children over 2 years old)
- Bipolar disorder (to help prevent episodes of depression and stabilise mood)
Who can take lamotrigine?
Lamotrigine is suitable for most adults and children over 2 years old with epilepsy or bipolar disorder.
Who might not be able to take lamotrigine?
Lamotrigine may not be suitable if you:
- Have liver or kidney disease
- Have a history of severe skin reactions
- Are taking certain other epilepsy or mental health medications
Can I take lamotrigine if I’m pregnant or breastfeeding?
Lamotrigine can be used during pregnancy, but your doctor may adjust your dose. If you are breastfeeding, small amounts can pass into breast milk, so speak to your doctor about potential risks.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is lamotrigine?
Lamotrigine is highly effective at preventing seizures and stabilising mood in bipolar disorder when taken regularly.
What should I do if I take too much?
Taking too much lamotrigine can be dangerous and may cause:
- Severe dizziness or drowsiness
- Seizures
- Rapid, uncontrollable eye movements
If you think you’ve taken too much, seek emergency medical help immediately.
What dose of lamotrigine is usually taken?
- For epilepsy: Starting dose is 25mg once daily, gradually increasing as advised by a doctor
- For bipolar disorder: Starting dose is 25mg once daily, increasing to 100mg to 400mg daily, depending on response
Your doctor will determine the best dose based on your condition.
What are the side effects of lamotrigine?
Common side effects include:
- Headache
- Dizziness or drowsiness
- Nausea
- Tremors
- Difficulty sleeping
Serious side effects, such as severe skin rashes (Stevens-Johnson syndrome) or suicidal thoughts, require urgent medical attention.
How should I take lamotrigine?
Lamotrigine is taken as tablets, chewable tablets, or dispersible tablets (which dissolve in water). Follow your doctor’s instructions carefully.
When should lamotrigine be taken?
Lamotrigine is usually taken once or twice daily, at the same time each day.
What are the brand names for lamotrigine?
Lamotrigine is available as a generic medicine, but some branded versions include:
- Lamictal
Final thoughts
Lamotrigine is an effective treatment for epilepsy and bipolar disorder, but it must be taken exactly as prescribed. If you experience side effects or need to stop taking it, speak to your doctor or pharmacist.
