Trazodone

Trazodone is a medication used to treat depression and sometimes prescribed for anxiety and sleep disorders. It helps improve mood and sleep by affecting serotonin levels in the brain. If you’ve been prescribed trazodone, here’s what you need to know.

What is trazodone?

Trazodone is an antidepressant that belongs to the serotonin antagonist and reuptake inhibitor (SARI) class. It helps regulate mood and can also be used as a sedative for sleep problems.

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How does trazodone work?

Trazodone increases serotonin levels in the brain, helping to improve mood and reduce anxiety. It also has a sedative effect, making it useful for people with sleep difficulties.

What is trazodone used to treat?

Trazodone is commonly prescribed for:

Who can take trazodone?

Trazodone is suitable for most adults who need treatment for depression, anxiety, or sleep disorders.

Who might not be able to take trazodone?

Trazodone may not be suitable if you:

Can I take trazodone if I’m pregnant or breastfeeding?

Trazodone isn’t usually recommended during pregnancy or while breastfeeding, but your doctor will assess whether the benefits outweigh the risks.

What if I miss a dose?

If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.

How effective is trazodone?

Trazodone is effective for depression and sleep issues, but it may take 2 to 4 weeks to see full benefits.

What should I do if I take too much?

Taking too much trazodone can be dangerous and may cause:

If you think you’ve taken too much, seek emergency medical help immediately.

What dose of trazodone is usually taken?

  • For depression: Starting dose of 150mg daily, increasing up to 300mg to 400mg daily if needed
  • For sleep problems: 25mg to 100mg before bedtime
  • For anxiety: 75mg to 150mg daily

Your doctor will determine the best dose for your condition.

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What are the side effects of trazodone?

Common side effects include:

Serious side effects, such as heart rhythm problems or severe mood changes, require urgent medical attention.

How should I take trazodone?

Trazodone is taken as tablets or liquid, usually once or twice daily. It should be taken with food to reduce stomach upset.

When should trazodone be taken?

Trazodone is usually taken in the evening, especially if used for sleep, but your doctor may recommend a different schedule depending on your condition.

What are the brand names for trazodone?

Trazodone is available as a generic medicine, but some branded versions include:

  • Molipaxin
  • Desyrel (outside the UK)

Final thoughts

Trazodone is an effective treatment for depression, anxiety, and sleep problems, but it should be taken exactly as prescribed. If you experience side effects or need to stop taking it, speak to your doctor or pharmacist.

Always consult a medical professional
This article is for informational purposes only and is not a substitute for medical advice. Always consult a healthcare professional before starting, stopping or changing any medication. If you have concerns about your medication or experience side effects, speak to your doctor or pharmacist immediately.

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