Mirtazapine

Mirtazapine is a medication used to treat depression and anxiety. It helps improve mood, sleep, and appetite in people experiencing low mood or emotional distress. If you’ve been prescribed mirtazapine, here’s what you need to know.

What is mirtazapine?

Mirtazapine is an antidepressant that belongs to the noradrenergic and specific serotonergic antidepressant (NaSSA) class. It works differently from many other antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs).

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How does mirtazapine work?

Mirtazapine increases the levels of serotonin and noradrenaline in the brain, chemicals that help regulate mood and emotions. It also has sedative effects, which can help with sleep problems.

What is mirtazapine used to treat?

Mirtazapine is prescribed for:

Who can take mirtazapine?

Mirtazapine is usually prescribed to adults, though in some cases, doctors may recommend it for younger people under close supervision.

Who might not be able to take mirtazapine?

Mirtazapine may not be suitable if you:

  • Are allergic to mirtazapine or similar medicines
  • Have bipolar disorder (without medical advice)
  • Have liver or kidney disease
  • Have a history of seizures or epilepsy
  • Have low sodium levels in your blood

Can I take mirtazapine if I’m pregnant or breastfeeding?

Mirtazapine is sometimes prescribed during pregnancy, but only if the benefits outweigh the risks. If you are pregnant, trying for a baby, or breastfeeding, speak to your doctor before taking it.

What if I miss a dose?

If you forget to take a dose, take it as soon as you remember unless it’s close to your next dose – do not double up to make up for a missed dose.

How effective is mirtazapine?

Mirtazapine is highly effective for depression and anxiety but does not work immediately. Most people begin to notice improvements in 2 to 4 weeks, with full effects developing over 6 to 8 weeks.

What should I do if I take too much?

Taking too much mirtazapine may cause drowsiness, confusion, or irregular heartbeats. If you think you’ve taken too much, seek medical help immediately.

What dose of mirtazapine is usually taken?

  • Starting dose: 15mg once daily (usually taken at night)
  • Maintenance dose: 15mg to 45mg once daily, adjusted as needed

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What are the side effects of mirtazapine?

Common side effects include:

  • Feeling drowsy or tired (especially at the start of treatment)
  • Increased appetite and weight gain
  • Dizziness
  • Dry mouth
  • Strange or vivid dreams

Some people experience more serious side effects, such as suicidal thoughts (especially in the first few weeks). If you feel unsafe, speak to a healthcare professional immediately.

How should I take mirtazapine?

Mirtazapine is taken as a tablet or dissolvable tablet, usually once a day before bedtime due to its sedative effects.

When should mirtazapine be taken?

Mirtazapine is usually taken in the evening, as it can make you feel sleepy.

What are the brand names for mirtazapine?

Mirtazapine is available under different brand names, including:

  • Zispin
  • Remeron

Final thoughts

Mirtazapine is an effective antidepressant, especially for those struggling with sleep and appetite changes due to depression. If prescribed, take it as directed, and speak to your doctor if you have concerns about side effects or stopping treatment.

Always consult a medical professional
This article is for informational purposes only and is not a substitute for medical advice. Always consult a healthcare professional before starting, stopping or changing any medication. If you have concerns about your medication or experience side effects, speak to your doctor or pharmacist immediately.

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