How does pregabalin work?
Pregabalin works by reducing the release of certain neurotransmitters involved in sending pain signals and triggering seizures. This helps calm overactive nerves and reduces symptoms of nerve pain, epilepsy, and anxiety.
What is pregabalin used to treat?
Pregabalin is used for:
- Nerve pain (e.g., pain from diabetes, shingles, or sciatica)
- Epilepsy (to help prevent seizures, usually alongside other medicines)
- Generalised anxiety disorder (GAD) (to reduce feelings of excessive worry and tension)
- Fibromyalgia (a condition causing widespread pain and tenderness)
Who can take pregabalin?
Pregabalin is usually prescribed for adults over 18, though it can be given to children for epilepsy in some cases.
Who might not be able to take pregabalin?
Pregabalin may not be suitable if you:
- Have had an allergic reaction to pregabalin or similar medicines
- Have a history of drug or alcohol dependence
- Have kidney disease (as your dose may need adjusting)
- Are taking other medications that cause drowsiness or dizziness
Can I take pregabalin if I’m pregnant or breastfeeding?
Pregabalin isn’t usually recommended during pregnancy, as there may be risks to the baby. If you’re pregnant or planning a pregnancy, speak to your doctor. It may also pass into breast milk, so check with your healthcare provider if you’re breastfeeding.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s nearly time for your next dose, skip the missed one—don’t take two doses at once.
How effective is pregabalin?
Pregabalin can significantly reduce nerve pain, control seizures, and ease anxiety, but it may take a few weeks to feel the full benefits. Stick to your prescribed dose, and let your doctor know if you don’t see improvements.
What should I do if I take too much pregabalin?
Taking too much can cause severe drowsiness, confusion, difficulty breathing, or even loss of consciousness. If you think you’ve taken too much, seek medical help immediately.
What dose of pregabalin is usually taken?
Doses vary depending on the condition:
- Nerve pain & anxiety: 150mg to 600mg daily, split into two or three doses
- Epilepsy: 150mg to 600mg daily, taken in divided doses
Your doctor will start you on a low dose and increase it gradually if needed.
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What are the side effects of pregabalin?
Common side effects include:
- Feeling drowsy or dizzy
- Weight gain
- Swelling in hands or feet
- Blurred vision
- Dry mouth
Some people may experience serious side effects like allergic reactions or suicidal thoughts. If you feel unwell or have mood changes, contact a doctor straight away.
How should I take pregabalin?
Pregabalin comes in capsules or a liquid and is usually taken twice or three times a day.
When should pregabalin be taken?
Pregabalin should be taken at evenly spaced times throughout the day to keep a steady level in your body. Taking it at the same times each day can help you remember.
What are the brand names for pregabalin?
Pregabalin is available under the brand name Lyrica in the UK.
Final thoughts
Pregabalin can be a life-changing medication for nerve pain, epilepsy, and anxiety, but it should be taken as prescribed. Some people may experience side effects, so regular check-ins with your doctor can help ensure it’s working well for you. If you have any concerns, speak to a healthcare professional.
