How does olanzapine work?
Olanzapine blocks dopamine and serotonin receptors, helping to reduce psychotic symptoms, stabilise mood, and prevent extreme highs and lows in bipolar disorder.
What is olanzapine used to treat?
Olanzapine is commonly prescribed for:
- Schizophrenia (to manage delusions, hallucinations, and disorganised thinking)
- Bipolar disorder (to stabilise mood and prevent manic episodes)
- Severe depression (as an add-on treatment in some cases)
Who can take olanzapine?
Olanzapine is suitable for most adults and some teenagers over 13 years old, depending on the condition being treated.
Who might not be able to take olanzapine?
Olanzapine may not be suitable if you:
- Have heart disease, high cholesterol, or a history of stroke
- Have diabetes or a high risk of diabetes
- Have a history of seizures or epilepsy
- Have glaucoma or liver disease
Can I take olanzapine if I’m pregnant or breastfeeding?
Olanzapine isn’t usually recommended during pregnancy or while breastfeeding unless the benefits outweigh the risks. Speak to your doctor if you are pregnant or planning to conceive.
What if I miss a dose?
If you forget a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—do not take two doses at once.
How effective is olanzapine?
Olanzapine is highly effective in managing symptoms of schizophrenia and bipolar disorder, but it may take a few weeks to see full benefits.
What should I do if I take too much?
Taking too much olanzapine can be dangerous and may cause:
- Severe drowsiness or confusion
- Low blood pressure
- Seizures or irregular heartbeat
If you think you’ve taken too much, seek emergency medical help immediately.
What dose of olanzapine is usually taken?
- For schizophrenia: 5mg to 20mg once daily
- For bipolar disorder: 5mg to 15mg once daily
- For depression (as an add-on treatment): Dose varies depending on the individual
Your doctor will determine the most suitable dose based on your condition.
Powered by pharmacies
With over 1,700 pharmacy partners across the UK, you can get the help you need, wherever you are based.
Our website and mobile app make it easy and convenient to manage your health needs and book services at a pharmacy nearby.
What are the side effects of olanzapine?
Common side effects include:
- Weight gain
- Drowsiness or dizziness
- Increased appetite
- Dry mouth
- Constipation
Serious side effects, such as severe mood changes, difficulty breathing, or high blood sugar, require urgent medical attention.
How should I take olanzapine?
Olanzapine is taken as tablets or orodispersible tablets (which dissolve in the mouth), usually once daily.
When should olanzapine be taken?
Olanzapine is usually taken at the same time each day, often in the evening due to its sedative effects.
What are the brand names for olanzapine?
Olanzapine is available as a generic medicine, but some branded versions include:
- Zyprexa
- Velotab
Final thoughts
Olanzapine is an effective treatment for schizophrenia and bipolar disorder, but it should be taken exactly as prescribed. If you experience side effects or need to stop taking it, speak to your doctor or pharmacist.
